Cardiovascular diseases (CVD) are one of the leading health problems worldwide. Elevated blood pressure remains the first and foremost modifiable risk factor for CVD and it is intimately associated with vascular function, lipid metabolism, inflammation, and oxidative stress conditions. The consumption of dairy proteins as part of the habitual diet may have beneficial impact on cardiometabolic health as well as in the prevention of cardiometabolic disease. This chapter reviews the main evidence on the impact of casein and whey proteins on human cardiovascular health. Evidence from long-term clinical studies assessing the effect of the chronic consumption of milk protein, although not conclusive, suggests they can reduce blood pressure and in some cases improve vascular function. During chronic milk protein consumption, dyslipidaemia also seems to be controlled. Short-term clinical studies mainly suggest benefits in vascular function and in lipid metabolism. However, comparison of the relative outcomes from these trials is difficult owing to variation in the form of measurement and inconsistent methods of assessing vascular function. More studies are needed including those examining the mechanisms underlying the action of milk proteins on the cardiometabolic health.

Milk proteins: Their role in cardiovascular health / C. Giromini, Á.A. Fekete, L. Pinotti, A. Baldi - In: Milk and Dairy Foods : Their Functionality in Human Health and Disease / [a cura di] I. Givens. - [s.l] : Elsevier, 2020. - ISBN 9780128156032. - pp. 145-172 [10.1016/B978-0-12-815603-2.00006-1]

Milk proteins: Their role in cardiovascular health

C. Giromini
Primo
;
L. Pinotti;A. Baldi
2020

Abstract

Cardiovascular diseases (CVD) are one of the leading health problems worldwide. Elevated blood pressure remains the first and foremost modifiable risk factor for CVD and it is intimately associated with vascular function, lipid metabolism, inflammation, and oxidative stress conditions. The consumption of dairy proteins as part of the habitual diet may have beneficial impact on cardiometabolic health as well as in the prevention of cardiometabolic disease. This chapter reviews the main evidence on the impact of casein and whey proteins on human cardiovascular health. Evidence from long-term clinical studies assessing the effect of the chronic consumption of milk protein, although not conclusive, suggests they can reduce blood pressure and in some cases improve vascular function. During chronic milk protein consumption, dyslipidaemia also seems to be controlled. Short-term clinical studies mainly suggest benefits in vascular function and in lipid metabolism. However, comparison of the relative outcomes from these trials is difficult owing to variation in the form of measurement and inconsistent methods of assessing vascular function. More studies are needed including those examining the mechanisms underlying the action of milk proteins on the cardiometabolic health.
Milk protein; Cardiovascular health; Blood pressure; Vascular function; Lipid metabolism; Inflammation; Oxidative stress
Settore AGR/18 - Nutrizione e Alimentazione Animale
2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/730477
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