Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the cloned TRPA1 channel when expressed in an heterologous cell system and are therefore suggested to be responsible for the chemesthetic properties of this plant.
Taste–guided identification of high potency TRPA1 agonists from Perilla frutescens / A. Bassoli, G. Borgonovo, S. Caimi, L. Scaglioni, G. Morini, A. Schiano Moriello, V. Di Marzo, L. De Petrocellis. - In: BIOORGANIC & MEDICINAL CHEMISTRY. - ISSN 0968-0896. - 17:4(2009), pp. 1636-1639.
Taste–guided identification of high potency TRPA1 agonists from Perilla frutescens
A. BassoliPrimo
;G. BorgonovoSecondo
;S. Caimi;L. Scaglioni;
2009
Abstract
Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the cloned TRPA1 channel when expressed in an heterologous cell system and are therefore suggested to be responsible for the chemesthetic properties of this plant.
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