Different epidemiological and preclinical studies have demonstrated that regular consumption of anthocyanin-rich foods is associated to a reduced risk of chronic diseases, such as cardiovascular diseases, cancer and obesity. However, assigning a health property to anthocyanins or other classes of flavonoids may be limited by the influence of other metabolites of plant-based food consumed in the diet, acting as possible confounding factors. The development of model foods essentially isogenic and nutritionally identical except that in the type and quantity of plant bioactives to be studied represents an important tool in nutritional studies. The extensive knowledge of the regulation of flavonoid pathway in maize can be exploited to obtain 'near-isogenic' model foods, which differ only in the content of specific classes of flavonoids. Being obtainable by breeding strategies, maize model foods can provide functional foods that can be used for both animal feeding studies and human intervention trials for assessing the role of flavonoids or other bioactives in preventing chronic diseases. This review will be focused on recent advances regarding the anthocyanin biosynthesis in maize, the role of anthocyanins from corn in preventing chronic diseases and finally on the breeding activities to produce maize functional foods with increased anthocyanin content.
Anthocyanins in corn : a wealth of genes for human health / K. Petroni, R. Pilu, C. Tonelli. - In: PLANTA. - ISSN 0032-0935. - 240:5(2014 Nov), pp. 901-911.
|Titolo:||Anthocyanins in corn : a wealth of genes for human health|
|Parole Chiave:||Chronic diseases; Functional food; Maize; Model food; Nutrigenomics|
|Settore Scientifico Disciplinare:||Settore BIO/18 - Genetica|
|Progetto:||AnThocyanin and polyphenol bioactives for Health Enhancement through Nutritional Advancement|
|Data di pubblicazione:||nov-2014|
|Data ahead of print / Data di stampa:||9-ago-2014|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s00425-014-2131-1|
|Appare nelle tipologie:||01 - Articolo su periodico|