SUIGO, LORENZO
SUIGO, LORENZO
Dipartimento di Scienze Farmaceutiche
Benzodioxane-benzamides targeting bacterial cell division protein FtsZ potentially disrupt SlmA-mediated nucleoid occlusion and reversible biomolecular condensation
2025 M. Sobrinos-Sanguino, I. Barros-Medina, L. Suigo, A. Lanzini, E. Valoti, W. Margolin, V. Straniero, B. Monterroso, S. Zorrilla
Targeting Bacterial Cell Division with Benzodioxane–Benzamide FtsZ Inhibitors as a Novel Strategy to Fight Gram-Positive Ovococcal Pathogens
2025 B. Furlan, M. Sobrinos-Sanguino, M. Sammartino, B. Monterroso, S. Zorrilla, A. Lanzini, L. Suigo, E. Valoti, O. Massidda, V. Straniero
DEVELOPMENT OF SMALL MOLECULES AS INHIBITORS OF FTSZ AND RNPA ACTING AS POTENTIAL ANTIMICROBIAL AGENTS
2023 L. Suigo
Benzodioxane–Benzamides as FtsZ Inhibitors: Effects of Linker’s Functionalization on Gram-Positive Antimicrobial Activity
2023 L. Suigo, W. Margolin, E. Ulzurrun, M. Hrast Rambaher, C. Zanotto, V. Sebastián-Pérez, N.E. Campillo, V. Straniero, E. Valoti
Benzodioxane-benzamides as promising inhibitors of Escherichia coli FtsZ
2023 L. Suigo, B. Monterroso, M. Sobrinos-Sanguino, C. Alfonso, V. Straniero, G. Rivas, S. Zorrilla, E. Valoti, W. Margolin
2-(1-Methoxycarbonyl-2-phenyleth-1-yl)-1-benzylpyridin-1-ium Bromide
2023 L. Suigo, V. Straniero, E. Valoti
PET Imaging of Innate Immune Activation Using 11C Radiotracers Targeting GPR84
2023 M. Kalita, J.H. Park, R.C. Kuo, S. Hayee, S. Marsango, V. Straniero, I.S. Alam, A. Rivera-Rodriguez, M. Pandrala, M.L. Carlson, S.T. Reyes, I.M. Jackson, L. Suigo, A. Luo, S.C. Nagy, E. Valoti, G. Milligan, F. Habte, B. Shen, M.L. James
Obtainment of Threo and Erythro Isomers of the 6-Fluoro-3-(2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxin-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide
2023 V. Straniero, L. Suigo, G. Lodigiani, E. Valoti
RESOLUTION VIA DIASTEREOMERIC AMIDES OF ENANTIOPURE 1,4-BENZOXATHIAN-2- AND 3-CARBOXYLIC ACIDS AND DETERMINATION OF THEIR CONFIGURATION
2022 G. Lodigiani, V. Straniero, L. Suigo, E. Valoti
Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice
2022 A. Casiraghi, F. Longhena, G. Faustini, G. Ribaudo, L. Suigo, G. Andrea Camacho-Hernandez, F. Bono, V. Brembati, A. Hauck Newman, A. Gianoncelli, V. Straniero, A. Bellucci, E. Valoti
Design, synthesis and antimicrobial evaluation of benzodioxane-benzamides FtsZ inhibitors: modification of the linker between the two scaffolds
2022 L. Suigo, V. Straniero, G. Lodigiani, C. Zanotto, M. Sobrinos-Sanguino, B. Monterroso, S. Zorrilla, G. Rivas, E. Valoti
RnpA inhibitors as potential antistaphylococcal agents: computational design, synthesis, and biological evaluation
2022 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, G. Lodigiani, P. Dunman, E. Valoti, V. Straniero
Development of a reliable synthetic scheme to isolate 2-hydroxy-2-benzodioxanylethoxy benzamides for the obtainment of fluorescent probles
2022 L. Suigo, V. Straniero, E. Valoti
Resolution via diastereomeric amides of enantiopure 1,4-benzoxathian-2- and 3-carboxylic acids and determination of their configuration
2022 V. Straniero, G. Lodigiani, L. Suigo, E. Valoti
(3-Methylene-2,3-dihydronaphtho[2,3-b][1,4]dioxin-2-yl)methanol
2022 L. Suigo, G. Lodigiani, V. Straniero, E. Valoti
Benzodioxane-benzamide FtsZ inhibitors: Synthesis of new derivatives and their biophysical and biochemical evaluation
2021 L. Suigo, M. Sobrinos-Sanguino, S. Zorilla, B. Monterroso, C. Alfonso, G. Rivas, V. Straniero, E. Valoti
Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket
2021 V. Straniero, V. Sebastián-Pérez, L. Suigo, W. Margolin, A. Casiraghi, M. Hrast, C. Zanotto, I. Zdovc, A. Radaelli, E. Valoti
RnpA inhibitors as potential antimicrobials to fight antibiotic-resistance: Computational design, synthesis, and biological evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. De Giuli Morghen, A. Casiraghi, P. Dunman, E. Valoti, V. Straniero
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. DE GIULI MORGHEN, A. Casiraghi, P.M. Dunman, E. Valoti, V. Straniero
Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ
2020 A. Casiraghi, L. Suigo, E. Valoti, V. Straniero