BROGGINI, LUCA
BROGGINI, LUCA
Dipartimento di Bioscienze
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024 M. Alberti, G. Poli, L. Broggini, S. Sainas, M. Rizzi, D. Boschi, D.M. Ferraris, E. Martino, S. Ricagno, T. Tuccinardi, M.L. Lolli, R. Miggiano
Multi-{eGO}: an in-silico lens to look into protein aggregation kinetics at atomic resolution
2022 E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Ba( (c))i('(c)) Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution
2022 E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Bačić Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni
L- to D-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics
2022 F. Ballabio, L. Broggini, C. Paissoni, X. Han, K. Peqini, B.M. Sala, R. Sun, T. Sandalova, A. Barbiroli, A. Achour, S. Pellegrino, S. Ricagno, C. Camilloni
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression
2021 D. Hofbauer, D. Mougiakakos, L. Broggini, M. Zaiss, M. Büttner-Herold, C. Bach, B. Spriewald, F. Neumann, S. Bisht, J. Nolting, R. Zeiser, S. Hamarsheh, M. Eberhardt, J. Vera, C. Visentin, C.M.G. De Luca, F. Moda, S. Haskamp, C. Flamann, M. Böttcher, K. Bitterer, S. Völkl, A. Mackensen, S. Ricagno, H. Bruns
MOLECULAR DETERMINANTS UNDERLYING PROTEIN MISFOLDING AND AGGREGATION
2021 L. Broggini
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
2020 C. Visentin, L. Musso, L. Broggini, F. Bonato, R. Russo, C. Moriconi, M. Bolognesi, E. Miranda, S. Dallavalle, D. Passarella, S. Ricagno
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity
2020 A. Achour, L. Broggini, X. Han, R. Sun, C. Santambrogio, J. Buratto, C. Visentin, A. Barbiroli, C.M.G. De Luca, P. Sormanni, F. Moda, A. De Simone, T. Sandalova, R. Grandori, C. Camilloni, S. Ricagno
Glycosylation Tunes Neuroserpin Physiological and Pathological Properties
2020 C. Visentin, L. Broggini, B.M. Sala, R. Russo, A. Barbiroli, C. Santambrogio, S. Nonnis, A. Dubnovitsky, M. Bolognesi, E. Miranda, A. Achour, S. Ricagno
Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State
2019 L. Visconti, F. Malagrinò, L. Broggini, C.R. DE LUCA, F. Moda, S. Gianni, S. Ricagno, A. Toto