GERMANO, GIOVANNI
GERMANO, GIOVANNI
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
2024 L. Lopez, L.G. Morosi, F. La Terza, P. Bourdely, G. Rospo, R. Amadio, G.M. Piperno, V. Russo, C. Volponi, S. Vodret, S. Joshi, F. Giannese, D. Lazarevic, G. Germano, P. Stoitzner, A. Bardelli, M. Dalod, L. Pace, N. Caronni, P. Guermonprez, F. Benvenuti
DNA repair-dependent immunogenic liabilities in colorectal cancer: opportunities from errors
2024 V. Amodio, P.P. Vitiello, A. Bardelli, G. Germano
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer
2024 G. Rospo, R. Chilà, V. Matafora, V. Basso, S. Lamba, A. Bartolini, A. Bachi, F. Di Nicolantonio, A. Mondino, G. Germano, A. Bardelli
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
2023 V. Amodio, S. Lamba, R. Chilà, C.M. Cattaneo, B. Mussolin, G. Corti, G. Rospo, E. Berrino, C. Tripodo, F. Pisati, A. Bartolini, M.C. Aquilano, S. Marsoni, G. Mauri, C. Marchiò, S. Abrignani, F. Di Nicolantonio, G. Germano, A. Bardelli
Unique Patterns of Heterogeneous Mismatch Repair Protein Expression in Colorectal Cancer Unveil Different Degrees of Tumor Mutational Burden and Distinct Tumor Microenvironment Features
2023 E. Berrino, M.C. Aquilano, E. Valtorta, V. Amodio, G. Germano, M. Gusmini, K. Gizzi, E. Fenocchio, A. Sapino, S. Marsoni, A. Sartore-Bianchi, A. Bardelli, S. Siena, E. Bonoldi, C. Marchiò
Temozolomide treatment alters mismatch repair and boosts mutational burden in tumor and blood of colorectal cancer patients
2022 G. Crisafulli, A. Sartore-Bianchi, L. Lazzari, F. Pietrantonio, A. Amatu, M. Macagno, L. Barault, A. Cassingena, A. Bartolini, P. Luraghi, G. Mauri, P. Battuello, N. Personeni, M.G. Zampino, V. Pessei, P.P. Vitiello, F. Tosi, L. Idotta, F. Morano, E. Valtorta, E. Bonoldi, G. Germano, F. Di Nicolantonio, S. Marsoni, S. Siena, A. Bardelli
Mechanisms of immune escape and resistance to checkpoint inhibitor therapies in mismatch repair deficient metastatic colorectal cancers
2021 V. Amodio, G. Mauri, N.M. Reilly, A. Sartore Bianchi, S. Siena, A. Bardelli, G. Germano
High-dose Vitamin C enhances cancer immunotherapy
2020 A. Magri, G. Germano, A. Lorenzato, S. Lamba, R. Chila, M. Montone, V. Amodio, T. Ceruti, F. Sassi, S. Arena, S. Abrignani, M. D'Incalci, M. Zucchetti, F. Di Nicolantonio, A. Bardelli
Evolving neoantigen profiles in colorectal cancers with DNA repair defects
2019 G. Rospo, A. Lorenzato, N. Amirouchene-Angelozzi, A. Magri, C. Cancelliere, G. Corti, C. Negrino, V. Amodio, M. Montone, A. Bartolini, L. Barault, L. Novara, C. Isella, E. Medico, A. Bertotti, L. Trusolino, G. Germano, F. Di Nicolantonio, A. Bardelli
Inactivation of DNA repair-prospects for boosting cancer immune surveillance
2018 A. Truini, G. Germano, A. Bardelli
The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2+ and CCR5+ IFNγ-producing γδT cells in mice
2018 R.C. Russo, B. Savino, M. Mirolo, C. Buracchi, G. Germano, A. Anselmo, L. Zammataro, F. Pasqualini, A. Mantovani, M. Locati, M.M. Teixeira
Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer
2018 G. Germano, G. Mauri, G. Siravegna, C. Dive, J. Pierce, F. Di Nicolantonio, M. D'Incalci, A. Bardelli, S. Siena, A. Sartore-Bianchi
SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo
2018 S. Mainardi, A. Mulero-Sánchez, A. Prahallad, G. Germano, A. Bosma, P. Krimpenfort, C. Lieftink, J.D. Steinberg, N. de Wit, S. Gonçalves-Ribeiro, E. Nadal, A. Bardelli, A. Villanueva, R. Bernards
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
2017 G. Germano, S. Lamba, G. Rospo, L. Barault, A. Magrì, F. Maione, M. Russo, G. Crisafulli, A. Bartolini, G. Lerda, G. Siravegna, B. Mussolin, R. Frapolli, M. Montone, F. Morano, F. de Braud, N. Amirouchene-Angelozzi, S. Marsoni, M. D'Incalci, A. Orlandi, E. Giraudo, A. Sartore-Bianchi, S. Siena, F. Pietrantonio, F. Di Nicolantonio, A. Bardelli
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer
2016 B.O. Van Emburgh, S. Arena, G. Siravegna, L. Lazzari, G. Crisafulli, G. Corti, B. Mussolin, F. Baldi, M. Buscarino, A. Bartolini, E. Valtorta, J. Vidal, B. Bellosillo, G. Germano, F. Pietrantonio, A. Ponzetti, J. Albanell, S. Siena, A. Sartore-Bianchi, F. Di Nicolantonio, C. Montagut, A. Bardelli
PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs
2015 A. Prahallad, G.J.J.E. Heynen, G. Germano, S.M. Willems, B. Evers, L. Vecchione, V. Gambino, C. Lieftink, R.L. Beijersbergen, F. DI NICOLANTONIO, A. Bardelli, R. Bernards
Molecular links between inflammation
2015 P. Allavena, G. Germano, A. Mantovani
Role of macrophage targeting in the antitumor activity of trabectedin
2013 G. Germano, R. Frapolli, C. Belgiovine, A. Anselmo, S. Pesce, M. Liguori, E. Erba, S. Uboldi, M. Zucchetti, F. Pasqualini, M. Nebuloni, N. van Rooijen, R. Mortarini, L. Beltrame, S. Marchini, I. Fuso Nerini, R. Sanfilippo, P.G. Casali, S. Pilotti, C.M. Galmarini, A. Anichini, A. Mantovani, M. D'Incalci, P. Allavena
Chemokines in cancer related inflammation
2011 P. Allavena, G. Germano, F. Marchesi, A. Mantovani
Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma
2011 M. Liguori, G. Solinas, G. Germano, A. Mantovani, P. Allavena