SIENA, SALVATORE
SIENA, SALVATORE
Dipartimento di Oncologia ed Emato-Oncologia
Targeting HER2 in Metastatic Colorectal Cancer: Current Therapies, Biomarker Refinement, and Emerging Strategies
2025 C. Vaghi, F. Tosi, G. Mauri, E. Bonazzina, A. Amatu, K. Bencardino, D. Piscazzi, L. Roazzi, F. Villa, M. Maggi, L. Monti, A. Bombelli, G. Marrapese, S. Ghezzi, G. Patelli, J. Ros, E. Elez, A. Sartore-Bianchi, S. Siena
Impact of chemotherapy on humoral and cellular immune responses to COVID-19 vaccination in patients with solid tumors
2025 A. Favalli, G. Patelli, P. Gruarin, A. Gobbini, E. Pesce, S. Mariano, M. Bombaci, F. Vincenti, L. Donnici, S. Marchese, D. Piscazzi, A. Amatu, F. Tosi, S. Ghezzi, A. Pani, S. Principato, A. Lombardi, A. Bandera, S. Abrignani, S. Siena, A. Sartore-Bianchi, R. Grifantini
Summary of Research: Efficacy of Trastuzumab Deruxtecan in HER2-Expressing Solid Tumors by Enrollment HER2 IHC Status: Post Hoc Analysis of DESTINY-PanTumor02
2025 A. Oaknin, J. Lee, V. Makker, D. Oh, S. Banerjee, A. González-Martín, K.H. Jung, I. Ługowska, L. Manso, A. Manzano, B. Melichar, S. Siena, D. Stroyakovskiy, A. Fielding, S. Puvvada, A. Smith, F. Meric-Bernstam
Circulating blood biomarkers for minimal residual disease in hepatocellular carcinoma: A systematic review
2025 E. Galli, G. Patelli, F. Villa, N. Gri, C. Mazzarelli, I. Mangoni, C. Sgrazzutti, S. Ghezzi, A. Sartore-Bianchi, L.S. Belli, L. De Carlis, A. Vanzulli, S. Siena, K. Bencardino
Clinicopathological characterisation of MTAP alterations in gastrointestinal cancers
2025 G. Mauri, G. Patelli, L. Roazzi, E. Valtorta, A. Amatu, G. Marrapese, E. Bonazzina, F. Tosi, K. Bencardino, G. Ciarlo, E. Mariella, S. Marsoni, A. Bardelli, E. Bonoldi, A. Sartore-Bianchi, S. Siena
Clinical utility and future perspectives of liquid biopsy in colorectal cancer
2025 G. Patelli, L. Lazzari, G. Crisafulli, A. Sartore-Bianchi, A. Bardelli, S. Siena, S. Marsoni
Tumor "age" in early-onset colorectal cancer
2025 G. Mauri, G. Patelli, G. Crisafulli, S. Siena, A. Bardelli
Comprehensive genomic profiling by liquid biopsy in refractory metastatic colorectal cancer patients who are candidate for anti-EGFR rechallenge therapy: findings from the CAVE-2 GOIM trial
2025 D. Ciardiello, L. Boscolo Bielo, F. Pietrantonio, G. Martini, T. Troiani, E. Martinelli, S. Natangelo, M.F. Bosco, S. Pisconti, C. Nisi, G. Tortora, L. Salvatore, A. Sartore-Bianchi, S. Siena, L. Blasi, M. Messina, E. Ongaro, A. Zaniboni, C. Pinto, L. Antonuzzo, A. Avallone, N. Normanno, G. Santabarbara, M.G. Zampino, R. Berardi, A.A. Cogoni, S. Leo, C. Lotesoriere, T.P. Latiano, E. Maiello, N. Fazio, G. Curigliano, R. Bordonaro, F. De Vita, F. Ciardiello, S. Napolitano
Biomarker testing implementation for molecularly targeted therapy in non-small cell lung cancer patients
2025 D. Lorenzini, G. Gaudioso, A. Scardoni, L. Blandi, A. Del Gobbo, P. Rafaniello Raviele, S. Ferrero, S.M. Veronese, C. Lauricella, F. Pagni, D. Seminati, M. Miozzo, C. Pesenti, U. Gianelli, S. Buiatiotis, C. Fumagalli, E. Guerini Rocco, A. Rappa, M. Barberis, N. Fusco, A. Ranghiero, S. La Rosa, F. Sessa, D. Furlan, N. Sahnane, C. Patriarca, M.G. Cangi, A. Lume, C. Doglioni, M. Ponzoni, W. Vermi, M. Novali, M. Paulli, E. Boveri, L. Terracciano, S. Uccella, A. Destro, E. Tamborini, F. Perrone, F. Pasotti, F. Agustoni, F. De Braud, F. Grossi, S. Siena, G. Curigliano, S. Buoro, G. Pruneri
Immunocytokines in cancer treatment: A systematic review
2025 S. Agliardi, C. Veronese, F. Panzeri, S. Palazzini, G. Guarnieri, S. Loiacono, V. Martinelli, A.M. Potenza, E. Sbraga, E. Rissotto, E. Inglese, F. Tosi, F. Villa, G. Patelli, L. Monti, A. Pani, R. Danesi, D. Fornasari, S. Siena, A. Sartore-Bianchi
Characteristics and Survival Outcomes of Patients With Metastatic RET Fusion-Positive Solid Tumors Receiving Non-RET Inhibitor Standards of Care in a Real-World Setting
2024 A. Hackshaw, O. Fajardo, U. Dafni, H. Gelderblom, P. Garrido, S. Siena, M.H. Taylor, W. Bordogna, C. Nikolaidis
Trastuzumab deruxtecan in patients with HER2-positive advanced colorectal cancer (DESTINY-CRC02): primary results from a multicentre, randomised, phase 2 trial
2024 K. Raghav, S. Siena, A. Takashima, T. Kato, M. Van den Eynde, F. Pietrantonio, Y. Komatsu, H. Kawakami, M. Peeters, T. Andre, S. Lonardi, K. Yamaguchi, J. Tie, C.G. Castro, H. Hsu, J.H. Strickler, T. Kim, Y. Cha, D. Barrios, Q. Yan, T. Kamio, K. Kobayashi, A. Boran, M. Koga, J.D. Allard, T. Yoshino
Ongoing Clinical Trials and Future Research Scenarios of Circulating Tumor DNA for the Treatment of Metastatic Colorectal Cancer
2024 L. Roazzi, G. Patelli, K.B. Bencardino, A. Amatu, E. Bonazzina, F. Tosi, B. Amoruso, A. Bombelli, S. Mariano, S. Stabile, C. Porta, S. Siena, A. Sartore-Bianchi
HER2-related biomarkers predict clinical outcomes with trastuzumab deruxtecan treatment in patients with HER2-expressing metastatic colorectal cancer: biomarker analyses of DESTINY-CRC01
2024 S. Siena, K. Raghav, T. Masuishi, K. Yamaguchi, T. Nishina, E. Elez, J. Rodriguez, I. Chau, M. Di Bartolomeo, H. Kawakami, F. Suto, M. Koga, K. Inaki, Y. Kuwahara, I. Takehara, D. Barrios, K. Kobayashi, A. Grothey, T. Yoshino
The role of anti-EGFR rechallenge in metastatic colorectal cancer, from available data to future developments: A systematic review
2024 D. Ciardiello, G. Mauri, A. Sartore-Bianchi, S. Siena, M.G. Zampino, N. Fazio, A. Cervantes
Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial
2024 F. Meric-Bernstam, V. Makker, A. Oaknin, D. Oh, S. Banerjee, A. González-Martín, K.H. Jung, I. Ługowska, L. Manso, A. Manzano, B. Melichar, S. Siena, D. Stroyakovskiy, A. Fielding, Y. Ma, S. Puvvada, N. Shire, J. Lee
Curative immune checkpoint inhibitors therapy in patients with mismatch repair-deficient locally advanced rectal cancer: a real-world observational study
2024 F. Tosi, L. Salvatore, E. Tamburini, S. Artale, S. Lonardi, S. Marchetti, A. Pastorino, F. Pietrantonio, A. Puccini, F.L. Rojas-Llimpe, B. Vincenzi, S. Mariano, F. Negri, K. Bencardino, C. Pinto, C. Aschele, S. Siena
Efficacy of Trastuzumab Deruxtecan in HER2-Expressing Solid Tumors by Enrollment HER2 IHC Status: Post Hoc Analysis of DESTINY-PanTumor02
2024 A. Oaknin, J. Lee, V. Makker, D. Oh, S. Banerjee, A. González-Martín, K.H. Jung, I. Ługowska, L. Manso, A. Manzano, B. Melichar, S. Siena, D. Stroyakovskiy, A. Fielding, S. Puvvada, A. Smith, F. Meric-Bernstam
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition
2024 G. Corti, K. Buzo, E. Berrino, M. Miotto, M.C. Aquilano, M. Lentini, S.E. Bellomo, A. Lorenzato, A. Bartolini, G. Mauri, L. Lazzari, M. Russo, F. Di Nicolantonio, S. Siena, S. Marsoni, C. Marchiò, A. Bardelli, S. Arena
Brief Report: Updated Efficacy and Safety Data From an Integrated Analysis of Entrectinib in Locally Advanced/Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer
2024 Y. Fan, A. Drilon, C. Chiu, H.H.F. Loong, S. Siena, M. Krzakowski, R. Dziadziuszko, H. Zeuner, C. Xue, M.G. Krebs