CICCARELLI, FRANCESCA
CICCARELLI, FRANCESCA
Dipartimento di Oncologia ed Emato-Oncologia
Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma
2026 S.A. Zamani, L. Wu, E.L. Black, A. Bartram, A.W.T. Ng, M. Secrier, J.D. Perelman, A. Ustaoglu, E. Ococks, D. Jacobson, G. Devonshire, N. Grehan, B. Nutzinger, A. Freeman, A. Miremadi, M. O'Donovan, A.M. Frankell, S. Killcoyne, F. Bartlett, R.D. Petty, H. Coleman, D. Mcmanus, R. Turkington, A. Grabowska, K. Moorthy, C.J. Peters, G.B. Hanna, S. Lishman, S. Sothi, M. Scott, R. Haidry, L. Lovat, J. Saunders, P. Kaye, I. Soomro, S.L. Parsons, L. Sreedharan, B. Kumar, E. Cheong, D. Chan, R. Berrisford, G. Sanders, F.D. Ciccarelli, V. Goh, U. Mahadeva, F. Chang, A. Davies, J. Gossage, J. Lagergren, B.L. Grace, R.C. Walker, T.J. Underwood, G. Contino, S. Puig, P. Taniere, A. Beggs, O. Tucker, J.R. O'Neill, T.R. Hupp, R.J.E. Skipworth, V. Save, I. Bagwan, S.R. Preston, A. Sharrocks, Y. Ang, S.J. Hayes, V. Sujendran, A. Hindmarsh, P. Safranek, R.H. Hardwick, N. Carroll, C. Crichton, J. Davies, S. Jammula, M. Secrier, M. Eldridge, C. Millington, H. Coles, C. Cheah, M. Tripathi, S. Malhotra, E.C. Smyth, S. Abbas, C. Loreno, A.M. Redmond, B. Nutzinger, P.A.W. Edwards, H.G. Coleman, R.C. Fitzgerald
Cytokine preactivation and ADCC: a potent strategy for enhancing human NK cell effector functions against 3D tumor models
2026 A. Lopez-Pardo, A. Amarilla-Irusta, A. Iturbe-Larrondo, I.S. Juan, V. Sandá, O. Zenarruzabeitia, F.D. Ciccarelli, F. Borrego, L. Amo
Research priorities for cancers of the oesophagus and stomach: recommendations from a UK and Ireland patient and healthcare professional partnership exercise
2025 C. M Jones, W. Han Ng, L. Tincknell, D. P Mcclurg, E. Adam, P. Bhandari, K. Campbell, P. Chambers, F. Ciccarelli, H. G Coleman, T. Crosby, C. Doyle, J. M Dunn, J. Elliott, R. C Fitzgerald, K. G Foley, V. Goh, H. I Grabsch, T. A Graham, M. Grocott, S. Gwynne, J. Harvey, M. Jansen, P. Lagergren, C. Lamb, L. Leigh-Doyle, F. Malik, C. Mayland, M. Mccord, A. Moss, S. Mukherjee, R. Petty, S. Rananaware, J. Reid, G. Rubin, E. Smyth, N. J Trudgill, R. C Turkington, T. J Underwood, F. M Walter, J. Williams, C. J Peters
A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer
2025 A. Acha-Sagredo, P. Andrei, K. Clayton, E. Taggart, C. Antoniotti, C.A. Woodman, H. Afrache, C. Fourny, M. Armero, H.K. Moinudeen, M. Green, N. Bhardwaj, A. Mikolajczak, M. Rodriguez-Lopez, M. Crawford, E. Connick, S. Lim, P. Hobson, J. Linares, E. Ignatova, D. Pelka, E.C. Smyth, N. Diamantis, D. Sosnowska, M. Carullo, P. Ciraci, F. Bergamo, R. Intini, E. Nye, P. Barral, M. Mishto, J.N. Arnold, S. Lonardi, C. Cremolini, E. Fontana, M. Rodriguez-Justo, F.D. Ciccarelli
Cancer-associated fibroblasts are associated with neo-adjuvant treatment response in oesophageal adenocarcinoma
2025 R.C. Walker, S.P. Breininger, B.P. Sharpe, J. Harrington, I. Reddin, C. Tse, R. Rajak, A. Hayden, S. Rahman, B. Grace, F. Izadi, J. West, R.C. Fitzgerald, P.A.W. Edwards, N. Grehan, B. Nutzinger, C. Hughes, E. Fidziukiewicz, S. Macrae, A. Northrop, X. Li, A. Katz-Summercorn, S. Abbas, M. O'Donovan, A. Miremadi, S. Malhotra, M. Tripathi, E. Smyth, S. Tavaré, A.G. Lynch, M. Eldridge, M. Secrier, G. Devonshire, S. Jammula, A.M. Redmond, S. Killcoyne, A. Grantham, A. Blasco, J. Davies, C. Crichton, N. Carroll, P. Safranek, A. Hindmarsh, V. Sujendran, J.R. O'Neill, S.J. Hayes, Y. Ang, A. Sharrocks, S.R. Preston, S. Oakes, I. Bagwan, V. Save, R.J.E. Skipworth, T.R. Hupp, O. Tucker, A. Beggs, P. Taniere, S. Puig, G. Contino, B.L. Grace, H. Barr, N. Shepherd, O. Old, J. Lagergren, J. Gossage, A. Davies, F. Chang, J. Zylstra, U. Mahadeva, V. Goh, F.D. Ciccarelli, G. Sanders, R. Berrisford, C. Harden, M. Lewis, E. Cheong, B. Kumar, S.L. Parsons, I. Soomro, P. Kaye, J. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, S. Suortamo, S. Lishman, G.B. Hanna, C.J. Peters, K. Moorthy, A. Grabowska, R. Turkington, D. Mcmanus, H. Coleman, D. Khoo, W. Fickling, T.D.L. Crosby, R.D. Petty, M. Secrier, Z.S. Walters, M.J.J. Rose-Zerilli, T.J. Underwood
Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer
2025 P. Ganguli, C.C. Basanta, A. Acha-Sagredo, H. Misetic, M. Armero, A. Mendez, A. Zahra, G. Devonshire, G. Kelly, A. Freeman, M. Green, E. Nye, A. Bichisecchi, P. Bonfanti, N. Null, R.C. Fitzgerald, P.A.W. Edwards, N. Grehan, B. Nutzinger, A.M. Redmond, C. Loreno, S. Abbas, A. Freeman, E.C. Smyth, M. O'Donovan, A. Miremadi, S. Malhotra, M. Tripathi, H. Coles, C. Millington, M. Eldridge, M. Secrier, G. Devonshire, J. Davies, C. Crichton, N. Carroll, R.H. Hardwick, P. Safranek, A. Hindmarsh, V. Sujendran, S.J. Hayes, Y. Ang, A. Sharrocks, S.R. Preston, I. Bagwan, V. Save, R.J.E. Skipworth, T.R. Hupp, J.R. O'Neill, O. Tucker, A. Beggs, P. Taniere, S. Puig, G. Contino, T.J. Underwood, R.C. Walker, B.L. Grace, J. Lagergren, J. Gossage, A. Davies, F. Chang, U. Mahadeva, V. Goh, F.D. Ciccarelli, G. Sanders, R. Berrisford, D. Chan, E. Cheong, B. Kumar, L. Sreedharan, S.L. Parsons, I. Soomro, P. Kaye, J. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, S. Lishman, G.B. Hanna, C.J. Peters, K. Moorthy, A. Grabowska, R. Turkington, D. Mcmanus, H. Coleman, R.D. Petty, F. Bartlett, M. Rodriguez-Justo, J. Spencer, R.C. Fitzgerald, F.D. Ciccarelli
Tumor microenvironments with an active type I IFN response are sensitive to inhibitors of heme degradation
2025 D. Sosnowska, T.S. Cheung, J. Sarkar, J.W. Opzoomer, K.T. Feehan, J.E. Anstee, C.A. Woodman, M.R. Keddar, K. Clayton, S. Ali, W. Macmorland, D.D. Yang, J. Rosekilly, C.E. Gillett, F.D. Ciccarelli, R. Buus, J. Spicer, A. Grigoriadis, J.N. Arnold
A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium
2024 C.J. Peters, Y. Ang, F.D. Ciccarelli, H. Coles, H.G. Coleman, G. Contino, T. Crosby, G. Devonshire, M. Eldridge, A. Freeman, N. Grehan, M. Mccord, B. Nutzinger, S. Zamani, S.L. Parsons, R. Petty, A.D. Sharrocks, R.J.E. Skipworth, E.C. Smyth, I. Soomro, T.J. Underwood, P.A.W. Edwards, A.M. Redmond, C. Loreno, S. Abbas, M. O'Donovan, A. Miremadi, S. Malhotra, M. Tripathi, C. Cheah, C. Millington, M. Secrier, S. Jammula, J. Davies, C. Crichton, N. Carroll, R.H. Hardwick, P. Safranek, A. Hindmarsh, V. Sujendran, S.J. Hayes, S.R. Preston, I. Bagwan, V. Save, T.R. Hupp, J.R. O'Neill, O. Tucker, A. Beggs, P. Taniere, S. Puig, R.C. Walker, B.L. Grace, J. Lagergren, J.A. Gossage, A.R. Davies, F. Chang, U. Mahadeva, V. Goh, G. Sanders, R. Berrisford, D. Chan, E. Cheong, B. Kumar, L. Sreedharan, P. Kaye, J.H. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, S. Lishman, G.B. Hanna, K. Moorthy, A. Grabowska, R.C. Turkington, D. Mcmanus, F. Bartlett, R.C. Fitzgerald
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett's oesophagus surveillance: Individual-level data analysis
2024 E.L. Black, E. Ococks, G. Devonshire, A.W.T. Ng, M. O'Donovan, S. Malhotra, M. Tripathi, F. Ciccarelli, A. Miremadi, A. Freeman, H. Coles, R.C. Fitzgerald
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue
2024 L. Montorsi, M.J. Pitcher, Y. Zhao, C. Dionisi, A. Demonti, T.J. Tull, P. Dhami, R.J. Ellis, C. Bishop, J.D. Sanderson, S. Jain, D. D'Cruz, D.L. Gibbons, T.H. Winkler, M. Bemark, F.D. Ciccarelli, J. Spencer
Multi-Omic Analysis of Esophageal Adenocarcinoma Uncovers Candidate Therapeutic Targets and Cancer-Selective Posttranscriptional Regulation
2024 J. Robert O'Neill, M.Y. Mayordomo, G. Mitulovic, S. Al Shboul, G. Bedran, J. Faktor, L. Hernychova, L. Uhrik, M. Gomez-Herranz, M. Kocikowski, V. Save, B. Vojtesek, M.J. Arends, T. Hupp, J.A. Alfaro, R.C. Fitzgerald, P.A.W. Edwards, N. Grehan, B. Nutzinger, C. Loreno, A.M. Redmond, S. Abbas, A. Freeman, E.C. Smyth, M. O'Donovan, A. Miremadi, S. Malhotra, M. Tripathi, C. Cheah, H. Coles, C. Millington, G. Devonshire, M. Eldridge, M. Secrier, S. Jammula, J. Davies, C. Crichton, N. Carroll, R.H. Hardwick, P. Safranek, A. Hindmarsh, V. Sujendran, S.J. Hayes, Y. Ang, A. Sharrocks, S.R. Preston, I. Bagwan, V. Save, R.J.E. Skipworth, T.R. Hupp, J. Robert O'Neill, O. Tucker, A. Beggs, P. Taniere, S. Puig, G. Contino, T.J. Underwood, R.C. Walker, B.L. Grace, J. Lagergren, J. Gossage, A. Davies, F. Chang, U. Mahadeva, V. Goh, F.D. Ciccarelli, G. Sanders, R. Berrisford, D. Chan, E. Cheong, B. Kumar, L. Sreedharan, S.L. Parsons, I. Soomro, P. Kaye, J. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, S. Lishman, G.B. Hanna, C.J. Peters, K. Moorthy, A. Grabowska, R. Turkington, D. Mcmanus, H. Coleman, R.D. Petty, F. Bartlet
Disentangling oncogenic amplicons in esophageal adenocarcinoma
2024 A.W.T. Ng, D.P. Mcclurg, B. Wesley, S.A. Zamani, E. Black, A. Miremadi, O. Giger, R.T. Hoopen, G. Devonshire, A.M. Redmond, N. Grehan, S. Jammula, A. Blasko, X. Li, S. Aparicio, S. Tavaré, N. Null, P.A.W. Edwards, N. Grehan, B. Nutzinger, C. Loreno, S. Abbas, A. Freeman, E.C. Smyth, M. O'Donovan, A. Miremadi, S. Malhotra, M. Tripathi, C. Cheah, H. Coles, C. Millington, M. Eldridge, M. Secrier, S. Jammula, J. Davies, C. Crichton, N. Carroll, R.H. Hardwick, P. Safranek, A. Hindmarsh, V. Sujendran, S.J. Hayes, Y. Ang, A. Sharrocks, S.R. Preston, I. Bagwan, V. Save, R.J.E. Skipworth, T.R. Hupp, J.R. O'Neill, O. Tucker, A. Beggs, P. Taniere, S. Puig, G. Contino, T.J. Underwood, R.C. Walker, B.L. Grace, J. Lagergren, J. Gossage, A. Davies, F. Chang, U. Mahadeva, V. Goh, F.D. Ciccarelli, G. Sanders, R. Berrisford, D. Chan, E. Cheong, B. Kumar, L. Sreedharan, S.L. Parsons, I. Soomro, P. Kaye, J. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, S. Lishman, G.B. Hanna, C.J. Peters, K. Moorthy, A. Grabowska, R. Turkington, D. Mcmanus, H. Coleman, R.D. Petty, F. Bartlet, K. Nowicki-Osuch, R.C. Fitzgerald
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development
2023 L. Novellasdemunt, A. Kucharska, A. Baulies, C. Hutton, G. Vlachogiannis, D. Repana, A. Rowan, A. Suarez-Bonnet, F. Ciccarelli, N. Valeri, V.S.W. Li
Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment
2023 H. Misetic, M.R. Keddar, J. Jeannon, F.D. Ciccarelli
Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource
2022 L. Dressler, M. Bortolomeazzi, M.R. Keddar, H. Misetic, G. Sartini, A. Acha-Sagredo, L. Montorsi, N. Wijewardhane, D. Repana, J. Nulsen, J. Goldman, M. Pollitt, P. Davis, A. Strange, K. Ambrose, F.D. Ciccarelli
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells
2022 N. Lockwood, S. Martini, A. Lopez-Pardo, K. Deiss, H.A. Segeren, R.K. Semple, I. Collins, D. Repana, M. Cobbaut, T. Soliman, F. Ciccarelli, P.J. Parker
Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers
2022 E.F. Gunady, K.E. Ware, S. Hoskinson Plumlee, N. Devos, D. Corcoran, J. Prinz, H. Misetic, F.D. Ciccarelli, T.M. Harrison, J.L. Thorne, R. Schopler, J.I. Everitt, W.C. Eward, J.A. Somarelli
Somatic variation in normal tissues: friend or foe of cancer early detection?
2022 A. Acha-Sagredo, P. Ganguli, F.D. Ciccarelli
Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway
2022 J. Marinello, A. Arleo, M. Russo, M. Delcuratolo, F. Ciccarelli, Y. Pommier, G. Capranico
Reflected stemness as a potential driver of the tumour microenvironment
2022 F.S. Rodrigues, F.D. Ciccarelli, I. Malanchi