Objectives: To evaluate the performance of the LI-RADS v.2018 scale by comparing it with the Likert scale, in the characterization of liver lesions. Methods: A total of 39 patients with chronic liver disease underwent MR examination for characterization of 44 liver lesions. Images were independently analyzed by two radiologists using the LI-RADS scale and by another two radiologists using the Likert scale. The reference standard used was either histopathological evaluation or a 4-year MRI follow-up. Receiver operating characteristic analysis was performed. Results: The LI-RADS scale obtained an accuracy of 80%, a sensitivity of 72%, a specificity of 93%, a positive predictive value (PPV) of 93% and a negative predictive value (NPV) of 70%, while the Likert scale achieved an accuracy of 79%, a sensitivity of 73%, a specificity of 87%, a PPV of 89% and a NPV of 70%. The area under the curve (AUC) was 85% for the LI-RADS scale and 83% for the Likert scale. The inter-observer agreement was strong (k = 0.89) between the LI-RADS evaluators and moderate (k = 0.69) between the Likert evaluators. Conclusions: There was no statistically significant difference between the performances of the two scales; nevertheless, we suggest that the LI-RADS scale be used, as it appeared more objective and consistent.
Characterization of liver nodules in patients with chronic liver disease by MRI: performance of the Liver Imaging Reporting and Data System (LI-RADS v.2018) scale and its comparison with the Likert scale / A. Esposito, V. Buscarino, D. Raciti, E. Casiraghi, M. Manini, P. Biondetti, L. Forzenigo. - In: LA RADIOLOGIA MEDICA. - ISSN 0033-8362. - 125:1(2020 Jan), pp. 15-23.
|Titolo:||Characterization of liver nodules in patients with chronic liver disease by MRI: performance of the Liver Imaging Reporting and Data System (LI-RADS v.2018) scale and its comparison with the Likert scale|
ESPOSITO, ANDREA ALESSANDRO (Primo) (Corresponding)
BUSCARINO, VALENTINA (Secondo)
BIONDETTI, PIERPAOLO (Penultimo)
|Parole Chiave:||Carcinoma, hepatocellular; Data interpretation, statistical; Early detection of cancer; Liver cirrhosis; Magnetic resonance imaging; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Diagnosis, Differential; Female; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Observer Variation; Precancerous Conditions; Predictive Value of Tests; ROC Curve; Reference Standards; Retrospective Studies; Sensitivity and Specificity; Ultrasonography|
|Settore Scientifico Disciplinare:||Settore INF/01 - Informatica|
Settore MED/01 - Statistica Medica
|Data di pubblicazione:||gen-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s11547-019-01092-y|
|Appare nelle tipologie:||01 - Articolo su periodico|
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