A 75-year-old man presented to the emergency department with a 1-year history of 66-pound weight loss and alternating bowel habits. He was admitted to the hospital, where he underwent several examinations to investigate the presence of a malignancy. A colonoscopy, a gastroscopy, an ultrasound of the abdomen, and a contrast-enhanced CT scan of thorax and abdomen did not detect any neoplasia. The only findings consisted of a prostatic hypertrophy and a basal pleural-parenchymal hyperdensity in the left lung, which was described as the result of an infective process. Neoplastic markers CA19.9, carcinoembryonic antigen, neuron-specific enolase, and α-fetoprotein were also negative. Wide-spectrum blood tests were unremarkable, except for hypogammaglobulinemia and elevated β2 microglobulin.
Clinical reasoning: a 75-year-old man with parkinsonism, mood depression, and weight loss / E. Frattini, E. Monfrini, G. Bitetto, B. Ferrari, S. Arcudi, N. Bresolin, M.C. Saetti, A. Di Fonzo. - In: NEUROLOGY. - ISSN 0028-3878. - 90:12(2018 Mar 20), pp. 572-575. [10.1212/WNL.0000000000005177]
Clinical reasoning: a 75-year-old man with parkinsonism, mood depression, and weight loss
E. Frattini
Primo
;E. MonfriniSecondo
;S. Arcudi;N. Bresolin;M.C. SaettiPenultimo
;A. Di FonzoUltimo
2018
Abstract
A 75-year-old man presented to the emergency department with a 1-year history of 66-pound weight loss and alternating bowel habits. He was admitted to the hospital, where he underwent several examinations to investigate the presence of a malignancy. A colonoscopy, a gastroscopy, an ultrasound of the abdomen, and a contrast-enhanced CT scan of thorax and abdomen did not detect any neoplasia. The only findings consisted of a prostatic hypertrophy and a basal pleural-parenchymal hyperdensity in the left lung, which was described as the result of an infective process. Neoplastic markers CA19.9, carcinoembryonic antigen, neuron-specific enolase, and α-fetoprotein were also negative. Wide-spectrum blood tests were unremarkable, except for hypogammaglobulinemia and elevated β2 microglobulin.File | Dimensione | Formato | |
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