IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca
IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.
AIR nasce in UNIMI nel 2006 con lo scopo di raccogliere, documentare e conservare le informazioni sulla produzione scientifica dell'Università degli Studi di Milano e costituisce di fatto l'Anagrafe della ricerca dell'Ateneo.
EnglishBackground: The introduction of a camera-based dose-reduction strategy in myocardial perfusion imaging (MPI) clinical setting entails the definition of objective and reproducible criteria for establishing the amount of activity to be injected. Aim: The aim is to evaluate the impact of count statistics on the estimation of summed-scores (SS), end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF). Methods: Data rest/stress ECG-gated SPECT (2-day protocol and 8 MBq·kg−1) were acquired with Bright View gamma camera and Astonish algorithm for 40 normal-weight and 40 overweight patients. Assuming that count statistics of shorter acquisition time may simulate that of lower injected activity, three simultaneous scans (full-time, half-time, and quarter-time scans) were started at the same time but with different acquisition time/projection (30, 15 and 8 seconds). Results: A significant difference between SS values of half-time and quarter-time stress scans was found for overweight group (P = .006). Post hoc test showed significant differences for ESV (P < .05), EDV (P < .01) and EF (P < .05) between half-time and quarter-time scans for both patient groups. Conclusions: The reduction of the count-statistics to a quarter of the MPI reference influenced negatively the quantification in overweight patients. The decrease of radiopharmaceutical activity to 25% of the reference seems practicable for normal-weight patients, while it is more appropriate an activity reduction limited to 50% for overweight and obese patients.
| Titolo: | Comparative analysis of full-time, half-time, and quarter-time myocardial ECG-gated SPECT quantification in normal-weight and overweight patients |
| Autori: | LECCHI, MICHELA (Primo) DEL SOLE, ANGELO SILVESTRO (Ultimo) |
| Parole Chiave: | gated SPECT; iterative reconstruction; myocardial perfusion imaging; patient dose; quarter-time scan; cardiology and cardiovascular medicine; radiology, nuclear medicine and imaging |
| Settore Scientifico Disciplinare: | Settore MED/36 - Diagnostica per Immagini e Radioterapia |
| Data di pubblicazione: | 2016 |
| Rivista: | |
| Tipologia: | Article (author) |
| Data ahead of print / Data di stampa: | 2016 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s12350-015-0382-2 |
| Appare nelle tipologie: | 01 - Articolo su periodico |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Lecchi et al. - 2016 - Comparative analysis of full-time, half-time, and quarter-time myocardial ECG-gated SPECT quantification in norma.pdf | Publisher's version/PDF | Administrator Richiedi una copia |
Copyright © 2020