For several years our research group, composed of hematologists, biologists, biotechnologists, and technicians has investigated the physio-pathological mechanisms of thrombotic thrombocytopenica purpura (TTP) in order to improve the diagnostic and therapeutic approach for patients affected with this disease. As TTP is a rare illness, the collection, organization and accurate statistical analysis of as much pertinent clinical and laboratory data as possible will help provide answers to unsolved problems related to it. With this aim in mind, we have created an international TTP database including clinical, laboratory, genetic, and therapeutic information on over 250 patients from all over the world. However, this data is not yet statistically significant to lead to definitive solutions. This ambitious objective can be achieved by means of collaboration among clinics with the problem of managing TTP patients as well as research centres able to determine the factors involved in the pathogenesis of TTP.

Thrombotic Thrombocytopenic Purpura (TTP) Database [Dataset] / F. Peyvandi, I. Garagiola, A. Maino, S. Lavoretano, R. Lombardi, G. Merati, R. Palla, C. Valsecchi, P.M. Mannucci, L.A. Lotta, I. Mancini, B. Ferrari, A. Artoni, G. Casoli, S. Pontiggia, G. Bettoni. - Milan, 2007 Feb 01.

Thrombotic Thrombocytopenic Purpura (TTP) Database

F. Peyvandi;I. Garagiola;A. Maino;S. Lavoretano;G. Merati;R. Palla;C. Valsecchi;P.M. Mannucci;L.A. Lotta;I. Mancini;B. Ferrari;A. Artoni;G. Bettoni
2007-02-01

Abstract

For several years our research group, composed of hematologists, biologists, biotechnologists, and technicians has investigated the physio-pathological mechanisms of thrombotic thrombocytopenica purpura (TTP) in order to improve the diagnostic and therapeutic approach for patients affected with this disease. As TTP is a rare illness, the collection, organization and accurate statistical analysis of as much pertinent clinical and laboratory data as possible will help provide answers to unsolved problems related to it. With this aim in mind, we have created an international TTP database including clinical, laboratory, genetic, and therapeutic information on over 250 patients from all over the world. However, this data is not yet statistically significant to lead to definitive solutions. This ambitious objective can be achieved by means of collaboration among clinics with the problem of managing TTP patients as well as research centres able to determine the factors involved in the pathogenesis of TTP.
database ; ttp ; porpora trombotica trombocitopenica
Settore MED/09 - Medicina Interna
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/33413
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