A series of 24 lung cancer cases was studied: 12 epidermoid carcinomas, 9 adenocarcinomas, 2 giant-cell carcinomas and 1 carcinoid. The patients were staged on the basis of the TNM classification system as 9 stage I, 5 stage II, 9 stage III and 1 stage IV. Using fresh tumour cell samples 2 cell cultures were prepared for each patient: one to identify the percentage of S phase cells (Labelling Index) using the tritiated thymidine method and one for cytogenetic analysis. A gentic map was obtained in 6 cases and revealed no specific numerical or structural alterations. The Labelling Index (L.I.) was calculated for all patients and compared with all TNM parameters. This revealed a certain connection between L.I. and parameters T, SN and G but no link with parameters.
[Clinical significance of cell kinetics in lung cancer] / F. Grignani, F. Varoli, A. M. Lavezzi, S. M. Scalambra, C. Vergani, L. Maturri, G. C. Roviaro. - In: MINERVA MEDICA. - ISSN 0026-4806. - 80:3(1989 Mar), pp. 195-197.
|Titolo:||[Clinical significance of cell kinetics in lung cancer]|
VAROLI, FEDERICO (Secondo)
ROVIARO, GIAN CARLO (Ultimo)
|Parole Chiave:||Neoplasm Staging; Humans; Prognosis; Aged; Interphase; Carcinoma, Small Cell; Lung Neoplasms; Adult; Carcinoid Tumor; Follow-Up Studies; Middle Aged; Adenocarcinoma; Carcinoma, Squamous Cell; Cell Cycle|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
Settore MED/10 - Malattie dell'Apparato Respiratorio
Settore MED/21 - Chirurgia Toracica
Settore MED/06 - Oncologia Medica
|Data di pubblicazione:||mar-1989|
|Appare nelle tipologie:||01 - Articolo su periodico|