Our work on isolated rat intestine aimed at studying the hypothesis that the intestinal transport of manganese was carrier-mediated and, consequently, subjected to saturation. Our results confirm this hypothesis, assessing the concentration of carrier saturation for manganese at 0.5 mM. As this concentration, which may determine self-limitation in the intestinal absorption of this metal, is much higher than the maximal allowed concentration of the EEC Standard (50 mg/l), food and water should be carefully monitored for their manganese content in order to avoid reaching toxic concentrations in blood and tissues.
Intestinal absorption of manganese: an in vitro study / G. Testolin, S. Ciappellano, A. Alberio, F. Piccinini, P. LAILA, A. Jotti. - In: ANNALS OF NUTRITION AND METABOLISM. - ISSN 0250-6807. - 37:6(1993), pp. 289-94-294.
Titolo: | Intestinal absorption of manganese: an in vitro study |
Autori: | |
Parole Chiave: | Atomic absorption spectrometry; Intestinal absorption; Manganese |
Settore Scientifico Disciplinare: | Settore BIO/09 - Fisiologia |
Data di pubblicazione: | 1993 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1159/000177779 |
Appare nelle tipologie: | 01 - Articolo su periodico |