Our work on isolated rat intestine aimed at studying the hypothesis that the intestinal transport of manganese was carrier-mediated and, consequently, subjected to saturation. Our results confirm this hypothesis, assessing the concentration of carrier saturation for manganese at 0.5 mM. As this concentration, which may determine self-limitation in the intestinal absorption of this metal, is much higher than the maximal allowed concentration of the EEC Standard (50 mg/l), food and water should be carefully monitored for their manganese content in order to avoid reaching toxic concentrations in blood and tissues.

Intestinal absorption of manganese: an in vitro study / G. Testolin, S. Ciappellano, A. Alberio, F. Piccinini, P. LAILA, A. Jotti. - In: ANNALS OF NUTRITION AND METABOLISM. - ISSN 0250-6807. - 37:6(1993), pp. 289-94-294.

Intestinal absorption of manganese: an in vitro study

G. Testolin;S. Ciappellano;
1993

Abstract

Our work on isolated rat intestine aimed at studying the hypothesis that the intestinal transport of manganese was carrier-mediated and, consequently, subjected to saturation. Our results confirm this hypothesis, assessing the concentration of carrier saturation for manganese at 0.5 mM. As this concentration, which may determine self-limitation in the intestinal absorption of this metal, is much higher than the maximal allowed concentration of the EEC Standard (50 mg/l), food and water should be carefully monitored for their manganese content in order to avoid reaching toxic concentrations in blood and tissues.
Atomic absorption spectrometry; Intestinal absorption; Manganese
Settore BIO/09 - Fisiologia
1993
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/189117
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