Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), lipase from Candida cylindracea (CCL) and porcine pancreatic lipase (PPL) is described. The enantioselectivities of the enzymatic transformations and the absolute configurations of the resulting half-esters 2a-c were determined.

Stereoselective enzymatic hydrolysis of dimethyl meso-piperidine-3,5-dicarboxylates / B. Danieli, G. Lesma, D. Passarella, A. Silvani. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 7:2(1996), pp. 345-348. [10.1016/0957-4166(96)00002-X]

Stereoselective enzymatic hydrolysis of dimethyl meso-piperidine-3,5-dicarboxylates

B. Danieli
Primo
;
G. Lesma
Secondo
;
D. Passarella
Penultimo
;
A. Silvani
Ultimo
1996

Abstract

Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), lipase from Candida cylindracea (CCL) and porcine pancreatic lipase (PPL) is described. The enantioselectivities of the enzymatic transformations and the absolute configurations of the resulting half-esters 2a-c were determined.
Settore CHIM/06 - Chimica Organica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/176469
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