here is growing interest in dietary phytochemicals as potential cancer chemopreventive agents. Resveratrol (3,4′,5-trihydroxy-trans-stilbene), a naturally occurring phytoalexin that is present in grapes, red wine, berries and peanuts, has been studied extensively for its ability to interfere with multistage carcinogenesis. Resveratrol is known to have antioxidant, anti-inflammatory and antiproliferative effects on a variety of cancer cells in vitro and in various animal models. However, the effect(s) of resveratrol in vivo on humans are still controversial. This study discusses current knowledge with regard to the effects of resveratrol in relation to its potential as a chemopreventive and/or chemotherapeutic molecule against human gliomas.
The potential of resveratrol against human gliomas / N. Gagliano, G. Aldini, G. Colombo, R. Rossi, R. Colombo, M. Gioia, A. Milzani, I. Dalle-Donne. - In: ANTI-CANCER DRUGS. - ISSN 0959-4973. - 21:2(2010), pp. 140-150.
|Titolo:||The potential of resveratrol against human gliomas|
GAGLIANO, NICOLETTA (Corresponding)
ALDINI, GIANCARLO (Secondo)
MILZANI, ALDO DOMENICO GUIDO (Penultimo)
DALLE DONNE, ISABELLA (Ultimo)
|Parole Chiave:||Glioma; Oxidative stress; Resveratrol; Tumour progression|
|Settore Scientifico Disciplinare:||Settore CHIM/08 - Chimica Farmaceutica|
Settore BIO/06 - Anatomia Comparata e Citologia
|Data di pubblicazione:||2010|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1097/CAD.0b013e32833498f1|
|Appare nelle tipologie:||01 - Articolo su periodico|