To reduce structural biases of observational studies, the use of propensity score (PS), a subject's probability of receiving a specific treatment conditional on the observed covariates, has been proposed the use of the probability that a subject would have been treated allows to adjoust the estimation of the treatment effect, creating a "quasi randomized" trial. The three techniques in using PS (matching, stratification and regression adjustment) were here applied to compare intravenous and enteral approach for sedative therapy in ICU.
Propensity score to reduce bias in observational studies : the case of enteral sedation in ICU patients / F. Rapido, M. Umbrello, E. D'Angelo, G. Mistraletti, M. Gomarasca, D. Palmisano, L. Bolgiaghi, B. Salihovic, A. Morabito, G. Iapichino. ((Intervento presentato al 21. convegno SMART tenutosi a Milano nel 2010.
Propensity score to reduce bias in observational studies : the case of enteral sedation in ICU patients
F. RapidoPrimo
;M. UmbrelloSecondo
;G. Mistraletti;D. Palmisano;A. MorabitoPenultimo
;G. IapichinoUltimo
2010
Abstract
To reduce structural biases of observational studies, the use of propensity score (PS), a subject's probability of receiving a specific treatment conditional on the observed covariates, has been proposed the use of the probability that a subject would have been treated allows to adjoust the estimation of the treatment effect, creating a "quasi randomized" trial. The three techniques in using PS (matching, stratification and regression adjustment) were here applied to compare intravenous and enteral approach for sedative therapy in ICU.Pubblicazioni consigliate
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