The effectiveness of nirsevimab in preventing the burden of respiratory syncytial virus (RSV)-bronchiolitis was evaluated with a test-negative case-control study in 208 infants presenting to Emergency Department. The effectiveness was 82% against RSV infection, 78% against RSV-related hospitalization, and 84% against intensive care admission. These real-world data support its inclusion in Italian immunization programs.
Effectiveness of Nirsevimab in preventing respiratory Syncytial virus-related burden: A test-negative case-control study in infants with bronchiolitis in Lombardy Region, Italy / E. Fusco, M. Loiodice, A. Romero, S. L'Assainato, A. Banfi, G.L. Chiaffoni, C. Porro, V. Fabiano, F. Izzo, V. De Giorgis, F. Forlanini, L. Barcellini, G. Zuccotti, L. Folgori. - In: THE PEDIATRIC INFECTIOUS DISEASE JOURNAL. - ISSN 0891-3668. - (2025), pp. 1-3. [Epub ahead of print] [10.1097/inf.0000000000004968]
Effectiveness of Nirsevimab in preventing respiratory Syncytial virus-related burden: A test-negative case-control study in infants with bronchiolitis in Lombardy Region, Italy
M. Loiodice;A. Romero;S. L'Assainato;A. Banfi;G.L. Chiaffoni;C. Porro;V. Fabiano;F. Izzo;V. De Giorgis;F. Forlanini;L. Barcellini;G. Zuccotti;
2025
Abstract
The effectiveness of nirsevimab in preventing the burden of respiratory syncytial virus (RSV)-bronchiolitis was evaluated with a test-negative case-control study in 208 infants presenting to Emergency Department. The effectiveness was 82% against RSV infection, 78% against RSV-related hospitalization, and 84% against intensive care admission. These real-world data support its inclusion in Italian immunization programs.
| File | Dimensione | Formato | |
|---|---|---|---|
|
PIDJ 2025 -2.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Licenza:
Nessuna licenza
Dimensione
297.31 kB
Formato
Adobe PDF
|
297.31 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
