SPARATORE, ANNA CONCETTINA
SPARATORE, ANNA CONCETTINA
Dipartimento di Scienze Farmaceutiche
Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities
2023 N. Basilico, S. Parapini, S. D’Alessandro, P. Misiano, S. Romeo, G. Dondio, V. Yardley, L. Vivas, S. Nasser, L. Rénia, B.M. Russell, R. Suwanarusk, F. Nosten, A. Sparatore, D. Taramelli
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis
2022 S. Marino, N. Hannemann, R.T. Bishop, F. Zeng, G. Carrasco, S. Meurisse, B. Li, A. Sophocleous, A. Sparatore, T. Baeuerle, S. Vukicevic, M. Auberval, P. Mollat, A. Bozec, A.I. Idris
MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment
2021 H. Rezai, S. Ahmad, F.A. Alzahrani, L. Sanchez-Aranguren, I.H. Dias, S. Agrawal, A. Sparatore, K. Wang, A. Ahmed
Superior Properties of N-Acetylcysteine Ethyl Ester over N-Acetyl Cysteine to Prevent Retinal Pigment Epithelial Cells Oxidative Damage
2021 G.M. Tosi, D. Giustarini, L. Franci, A. Minetti, F. Imperatore, E. Caldi, P. Fiorenzani, A. Maria Aloisi, A.C. Sparatore, R. Rossi, M. Chiariello, M. Orlandini, F. Galvagni
Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo
2021 A. Koval, I. Bassanini, J. Xu, M. Tonelli, V. Boido, F. Sparatore, F. Amant, D. Annibali, E. Leucci, A. Sparatore, V.L. Katanaev
Hydrogen sulfide releasing molecule {MZe}786 inhibits soluble Flt-1 and prevents preeclampsia in a refined mouse {RUPP} model
2021 J. Saif, S. Ahmad, H. Rezai, K. Litvinova, A.C. Sparatore, F.A. Alzahrani, K. Wang, A. Ahmed
Design, Synthesis and In Vitro Investigation of Novel Basic Celastrol Carboxamides as Bio-Inspired Leishmanicidal Agents Endowed with Inhibitory Activity against Leishmania Hsp90
2021 I. Bassanini, S. Parapini, E.E. Ferrandi, E. Gabriele, N. Basilico, D. Taramelli, A.C. Sparatore
Quinolizidine-derived lucanthone and amitriptyline analogues endowed with potent antileishmanial activity
2020 M. Tonelli, A. Sparatore, N. Basilico, L. Cavicchini, S. Parapini, B. Tasso, E. Laurini, S. Pricl, V. Boido, F. Sparatore
Combined administration of a small-molecule inhibitor of TRAF6 and Docetaxel reduces breast cancer skeletal metastasis and osteolysis
2020 R.T. Bishop, S. Marino, G. Carrasco, B. Li, R.J. Allen, A. Sparatore, P.D. Ottewell, P. Mollat, A.H. Sims, M. Capulli, N. Wang, A.I. Idris
MZe786 Rescues Cardiac Mitochondrial Activity in High sFlt-1 and Low HO-1 Environment
2020 L.C. Sanchez-Aranguren, H. Rezai, S. Ahmad, F.A. Alzahrani, A. Sparatore, K. Wang, A. Ahmed
Disruption of prostate cancer cell—macrophage—osteoclast crosstalk by a novel TRAF6 inhibitor
2019 G. Carrasco, R. Bishop, A. Maurizi, M. Capulli, A. Sparatore, S. Marino, A.I. Idris
New hydrophilic riminophenazines as potent antiprotozoal agents
2019 I. Bassanini, S. Parapini, N. Basilico, A.C. Sparatore
Target-Oriented Development Of Novel Antiprotozoal Agents: Celastrol Carboxamides As Inhibitors Of Leishmania Hsp90
2019 I. Bassanini, E. Elisa Ferrandi, S. Parapini, N. Basilico, A.C. Sparatore
Novel Hydrophilic Riminophenazines as Potent Antiprotozoal Agents
2019 I. Bassanini, S. Parapini, N. Basilico, A.C. Sparatore
Benzimidazole derivatives endowed with potent antileishmanial activity
2018 T. Michele, E. Gabriele, P. Francesca, N. Basilico, S. Parapini, T. Bruno, L. Roberta, S. Fabio, A. Sparatore
The new H2S-releasing compound ACS94 exerts protective effects through the modulation of thiol homoeostasis
2018 D. Giustarini, V. Tazzari, I. Bassanini, R. Rossi, A. Sparatore
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline : A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial
2017 N. Basilico, S. Parapini, A. Sparatore, S. Romeo, P. Misiano, L. Vivas, V. Yardley, S..L. Croft, A. Habluetzel, L. Lucantoni, L. Renia, B. Russell, R. Suwanarusk, F. Nosten, G. Dondio, C. Bigogno, D. Jabes, D. Taramelli
New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors
2017 E. Gabriele, D. Brambilla, C. Ricci, L. Regazzoni, K. Taguchi, N. Ferri, A. Asai, A. Sparatore
Synthesis of new dithiolethione and methanethiosulfonate systems endowed with pharmaceutical interest
2017 E. Gabriele, F. Porta, G. Facchetti, C. Galli, A. Gelain, F. Meneghetti, I. Rimoldi, S. Romeo, S. Villa, C. Ricci, N. Ferri, A. Asai, D. Barlocco, A. Sparatore
Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain
2017 E. Gabriele, C. Ricci, F. Meneghetti, N. Ferri, A. Asai, A. Sparatore