IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

BORSARI, CHIARA
 Distribuzione geografica
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Continente #
AS - Asia 2.661
EU - Europa 1.374
NA - Nord America 1.248
SA - Sud America 370
AF - Africa 54
OC - Oceania 8
Totale 5.715
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Nazione #
US - Stati Uniti d'America 1.209
SG - Singapore 934
CN - Cina 883
IT - Italia 491
BR - Brasile 294
HK - Hong Kong 264
IN - India 179
RU - Federazione Russa 177
DE - Germania 156
VN - Vietnam 101
NL - Olanda 93
SE - Svezia 84
FR - Francia 75
GB - Regno Unito 65
ID - Indonesia 62
KR - Corea 54
CH - Svizzera 44
FI - Finlandia 39
JP - Giappone 37
AT - Austria 32
AR - Argentina 28
ES - Italia 23
BD - Bangladesh 22
TR - Turchia 22
PL - Polonia 19
PT - Portogallo 17
EC - Ecuador 15
MX - Messico 15
ZA - Sudafrica 15
IE - Irlanda 14
UA - Ucraina 13
IQ - Iraq 12
UZ - Uzbekistan 11
CO - Colombia 10
CA - Canada 9
CI - Costa d'Avorio 9
MA - Marocco 9
TW - Taiwan 9
IR - Iran 8
PK - Pakistan 8
MY - Malesia 7
AE - Emirati Arabi Uniti 6
PH - Filippine 6
PY - Paraguay 6
AU - Australia 5
CL - Cile 5
DZ - Algeria 5
JO - Giordania 5
SA - Arabia Saudita 5
TT - Trinidad e Tobago 5
AZ - Azerbaigian 4
DK - Danimarca 4
KE - Kenya 4
NP - Nepal 4
AL - Albania 3
BE - Belgio 3
BH - Bahrain 3
EG - Egitto 3
HR - Croazia 3
IL - Israele 3
JM - Giamaica 3
PE - Perù 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
UY - Uruguay 3
VE - Venezuela 3
CR - Costa Rica 2
CY - Cipro 2
CZ - Repubblica Ceca 2
GH - Ghana 2
GR - Grecia 2
KZ - Kazakistan 2
LT - Lituania 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
SI - Slovenia 2
SN - Senegal 2
SV - El Salvador 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BO - Bolivia 1
BZ - Belize 1
CD - Congo 1
EE - Estonia 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
MD - Moldavia 1
MZ - Mozambico 1
NG - Nigeria 1
PS - Palestinian Territory 1
RO - Romania 1
SC - Seychelles 1
SR - Suriname 1
TN - Tunisia 1
Totale 5.714
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Città #
Singapore 409
Hefei 324
Hong Kong 232
Milan 220
Dallas 202
Ashburn 171
Santa Clara 136
Bengaluru 119
Beijing 103
Los Angeles 92
Council Bluffs 81
Boardman 52
Jakarta 51
San Jose 46
Seoul 38
Frankfurt am Main 37
Monza 37
Buffalo 36
Nuremberg 36
Moscow 33
São Paulo 31
Hanoi 29
Ho Chi Minh City 29
Guangzhou 27
Munich 25
Rome 24
Cangzhou 23
New York 23
Tokyo 22
Basel 21
Helsinki 21
Vienna 18
Chicago 16
Dublin 16
Shanghai 14
Warsaw 14
Columbus 13
Lappeenranta 13
Amsterdam 11
Bologna 11
Chennai 11
Hamburg 11
Paris 11
Rio de Janeiro 11
Romola 10
Strasbourg 10
Tashkent 10
Abidjan 9
Houston 9
Orem 9
Atlanta 8
Chandler 8
Johannesburg 8
Southend 8
West Jordan 8
Zurich 8
Brooklyn 7
Kuala Lumpur 7
Lisbon 7
London 7
Porto 7
Tianjin 7
Da Nang 6
Denver 6
Fairfield 6
Istanbul 6
Lausanne 6
Seattle 6
Asunción 5
Baghdad 5
Belo Horizonte 5
Berlin 5
Brescia 5
Capelle aan den IJssel 5
Düsseldorf 5
Groningen 5
Guayaquil 5
Hyderabad 5
Kent 5
Montreal 5
Parma 5
Phoenix 5
Recife 5
Salt Lake City 5
Salvador 5
Shenzhen 5
Tehran 5
Wilmington 5
Amman 4
Ankara 4
Bergamo 4
Biên Hòa 4
Bodio Lomnago 4
Botucatu 4
Changsha 4
City of London 4
Dhaka 4
Edinburgh 4
Goiânia 4
Gurugram 4
Totale 3.231
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Nome #
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents 277
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 255
Chemo-enzymatic flow synthesis of nature-inspired phenolic carbonates and carbamates as antiradical and antimicrobial agents 207
Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives 189
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead 169
Tyrosol and hydroxytyrosol carbonates and carbamates as novel antiradical and antimicrobial agents: a chemo-enzymatic flow synthesis 160
Chemo-enzymatic flow synthesis of tyrosol and hydroxytyrosol carbonates and carbamates as novel antiradical and antimicrobial agents 156
Chemo-enzymatic flow synthesis of nature-inspired phenolic carbonates and carbamates as antimicrobial and antiradical agents 153
Chemo-enzymatic asymmetric flow synthesis of piperidine as pharmaceutically relevant scaffolds 143
Two-Step Flow Amidation of Natural Phenolic Acids as Antiradical and Antimicrobial Agents 142
METHOD FOR IDENTIFYING PI3 KINASE-ALPHA INHIBITORS | [VERFAHREN ZUR IDENTIFIZIERUNG VON PI3-KINASE-ALPHA-INHIBITOREN] 136
METHOD FOR IDENTIFYING PI3 KINASE-ALPHA INHIBITORS 127
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 122
A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα 121
TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K 121
TRIAZINE DERIVATIVE AS REVERSIBLE AND IRREVERSIBLE COVALENT INHIBITORS OF PI3K | [TRIAZINDERIVAT ALS REVERSIBLE UND IRREVERSIBLE KOVALENTE PI3K-HEMMER] 113
TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K 110
(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class i PI3K and mTOR Kinase 105
Targeted Covalent Inhibitors in Drug Discovery, Chemical Biology and Beyond 101
TRIAZINE DERIVATIVE AS REVERSIBLE AND IRREVERSIBLE COVALENT INHIBITORS OF PI3K 99
Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery 98
METHOD FOR IDENTIFYING PI3 KINASE-ALPHA INHIBITORS 95
Compounds having antiparasitic activity 94
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs 93
TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | [TRIAZINDERIVAT ALS KOVALENTE INHIBITOREN VON PI3K] 92
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity 89
Stereospecific Synthesis of Substituted Sulfamidates as Privileged Morpholine Building Blocks 89
4-(Difluoromethyl)-5-(4-((3 R,5 S)-3,5-dimethylmorpholino)-6-((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders 85
TRIAZINE DERIVATIVE AS REVERSIBLE AND IRREVERSIBLE COVALENT INHIBITORS OF PI3K 84
The Facets of Diversity: The EFMC Perspective 82
YMCC and YSN: An Opportunity for Scientific and Cultural Exchange 81
Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling 81
Highlights from the Lowlands: Early Career Researchers Shine at Medicinal Chemistry Frontiers 2024 80
Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood-brain barrier permeability 79
Boosting the Impact of EFMC Young Scientists Network Through the Creation of Working Groups 78
Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα 78
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase 75
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 66
A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor 66
Designing Chimeric Molecules for Drug Discovery by Leveraging Chemical Biology 65
Disease related mutations in PI3Kgamma disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors 65
Design, synthesis and antiparasitic evaluation of click phospholipids 64
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity 63
Chemical and Structural Strategies to Selectively Target mTOR Kinase 63
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor 63
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds 60
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 60
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 59
5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class i PI3K/mTOR Inhibitor as Clinical Candidate in Oncology 58
SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti- Trypanosoma brucei Agent 57
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 56
Targeting Phosphoinositide 3-Kinase – Five Decades of Chemical Space Exploration 56
Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders 55
Two-drug trick to target the brain blocks toxicity in the body 53
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 49
Preclinical Development of PQR514, a Highly Potent PI3K Inhibitor Bearing a Difluoromethyl-Pyrimidine Moiety 46
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics 46
Scalable, Economical, and Practical Synthesis of 4-(Difluoromethyl)pyridin-2-amine, a Key Intermediate for Lipid Kinase Inhibitors 46
Scaffolds and Biological Targets Avenue to Fight Against Drug Resistance in Leishmaniasis 43
YMCC and YSN: An Opportunity for Scientific and Cultural Exchange 43
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors 42
Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case 42
Target-based approaches for the discovery of new antimycobacterial drugs 39
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins 37
From Batch to Flow: Chemo-Enzymatic Asymmetric Synthesis of Piperidine Scaffolds 30
null 20
From pan-active to parasite-selective antiparasitic agents: A scaffold hopping approach 8
Totale 5.979
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Categoria #
all - tutte 21.274
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.274
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202126 0 0 0 0 0 0 4 5 7 2 8 0
2021/202239 2 2 4 8 5 0 3 2 2 0 7 4
2022/202364 4 3 2 3 3 7 4 2 5 1 25 5
2023/2024814 3 7 5 44 181 107 84 20 59 81 104 119
2024/20252.178 93 158 60 121 212 94 119 250 128 205 202 536
2025/20262.826 426 581 625 500 322 241 131 0 0 0 0 0
Totale 5.979