RONCHETTI, DOMENICA
RONCHETTI, DOMENICA
Dipartimento di Oncologia ed Emato-Oncologia
Exploring the role of NONO in transcriptional regulation of cellular pathways in Multiple Myeloma: insights into its paraspeckle-dependent and independent regulatory mechanisms
2025 E. Taiana, A. Devecchi, I. Silvestris, V. Traini, G. Fabbiano, M. Lionetti, M.C. Da Vià, N. Puccio, I. Craparotta, M. Bolis, R. Piva, A. Neri, L. Agnelli, F. Passamonti, N. Bolli, D. Ronchetti
Exploring the role of NONO in transcriptional regulation of cellular pathways in Multiple Myeloma: insights into its paraspeckle-dependent and independent regulatory mechanisms
2025 E. Taiana, A. Devecchi, I. Silvestris, V. Traini, G. Fabbiano, M. Lionetti, M.C. Da Vià, N. Puccio, I. Craparotta, M. Bolis, R. Piva, A. Neri, L. Agnelli, F. Passamonti, N. Bolli, D. Ronchetti
The biological relevance of upregulated NONO protein in multiple myeloma through the regulation of cell cycle progression and drug treatment response
2025 G. Fabbiano, V. Traini, I. Silvestris, D. Ronchetti, M. Barbieri, F. Lazzaroni, M. Scopetti, A. Matera, A. Maeda, F. Colombo, L. Porretti, F. Passamonti, N. Bolli, E. Taiana
In silico-identified putative inhibitors of paraspeckle assembly induce cell death by apoptosis in Multiple Myeloma cells and lead to the activation of the cGAS/STING pathway.
2025 V. Traini, D. Ronchetti, G. Fabbiano, I. Silvestris, N. Puccio, F. Torricelli, V. Manicardi, M. Barbieri, F. Colombo, L. Porretti, Y. Torrente, I. Eberini, F. Passamonti, N. Bolli, A. Neri, E. Taiana
Clonal hematopoiesis is clonally unrelated to multiple myeloma and is associated with specific microenvironmental changes
2025 M. Lionetti, M. Scopetti, A. Matera, A. Maeda, A. Marella, F. Lazzaroni, G. Castellano, S. Fabris, S. Pioggia, S. Lonati, A. Marchetti, A. Cattaneo, M. Tornese, A. Neri, C. Leoni, L. Pettine, V. Traini, I. Silvestris, M. Barbieri, G. Fabbiano, D. Ronchetti, E. Taiana, C. De Magistris, M.C. Da Via', F. Passamonti, N. Bolli
Biological and molecular characterization of in silico identified putative inhibitors of paraspeckle assembly with potential anti-multiple myeloma activity
2024 V. Traini, G. Fabbiano, D. Ronchetti, I. Silvestris, N. Puccio, S. Erratico, D. Giannandrea, T. Laurenzi, L. Palazzolo, A. Ciarrocchi, Y. Torrente, R. Chiaramonte, I. Eberini, N. Bolli, A. Neri, E. Taiana
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers
2024 D. Ronchetti, V. Traini, I. Silvestris, G. Fabbiano, F. Passamonti, N. Bolli, E. Taiana
DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification
2024 V.K. Favasuli, D. Ronchetti, I. Silvestris, N. Puccio, G. Fabbiano, V. Traini, K. Todoerti, S. Erratico, A. Ciarrocchi, V. Fragliasso, D. Giannandrea, F. Tumiatti, R. Chiaramonte, Y. Torrente, P. Finelli, E. Morelli, N.C. Munshi, N. Bolli, A. Neri, E. Taìana
Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma
2024 N. Puccio, G. Manzotti, E. Mereu, F. Torricelli, D. Ronchetti, M. Cumerlato, I. Craparotta, L.D. Rito, M. Bolis, V. Traini, V. Manicardi, V. Fragliasso, Y. Torrente, N. Amodio, N. Bolli, E. Taiana, A. Ciarrocchi, R. Piva, A. Neri
Investigation of the biological and molecular relevance of NONO protein in multiple myeloma
2024 V. Traini, G. Fabbiano, I. Silvestris, D. Ronchetti, M. Barbieri, F. Colombo, L. Porretti, Y. Torrente, F. Passamonti, N. Bolli, E. Taiana
NONO is required for multiple myeloma cell lines growth through stabilisation of lncRNA NEAT1 and paraspeckle integrity
2024 G. Fabbiano, V. Traini, D. Ronchetti, I. Silvestris, F. Lazzaroni, M. Barbieri, V.K. Favasuli, N. Puccio, F. Colombo, L. Porretti, Y. Torrente, A. Ciarrocchi, A. Neri, E. Morelli, F. Passamonti, N. Bolli, E. Taiana
Characterization of the biological and molecular relevance of nonoprotein in multiple myeloma
2024 G. Fabbiano, V. Traini, D. Ronchetti, I. Silvestris, M. Barbieri, F. Colombo, S. Erratico, V.K. Favasuli, N. Puccio, L. Porretti, Y. Torrente, A. Ciarrocchi, A. Neri, N. Bolli, E. Taiana
FUNCTIONAL DISSECTION OF THE SINGLE CELL TRANSCRIPTOMIC LANDSCAPE OF GENOTYPICALLY-IDENTIFIED POLYCLONAL PLASMACELLS IN MULTIPLE MYELOMA MICROENVIRONMENT
2024 F. Lazzaroni, M.C. Da Vià, A. Matera, A. Marella, A. Maeda, A. Marchetti, S. Fabris, S. Pioggia, I. Silvestris, D. Ronchetti, S. Lonati, G. Fabbiano, V. Traini, E. Taiana, G. Castellano, C. De Magistris, M. Scopetti, N. Puccio, F. Torricelli, M. Barbieri, L. Pettine, A. Neri, M. Lionetti, F. Passamonti, N. Bolli
FUNCTIONAL DISSECTION OF THE SINGLE CELL TRANSCRIPTOMIC LANDSCAPE OF GENOTYPICALLY-IDENTIFIED POLYCLONAL PLASMACELLS IN MULTIPLE MYELOMA MICROENVIRONMENT
2024 M.C. Da Vià, F. Lazzaroni, A. Matera, A. Marella, A. Maeda, A. Marchetti, S. Fabris, S. Pioggia, I. Silvestris, D. Ronchetti, S. Lonati, G. Fabbiano, V. Traini, E. Taiana, G. Castellano, C. Demagistris, M. Scopetti, N. Puccio, F. Torricelli, M. Barbieri, L. Pettine, A. Neri, M. Lionetti, F. Passamonti, N. Bolli
Inference of genomic lesions from single-cell RNA-seq in myeloma improves functional intraclonal and interclonal analysis
2024 F. Lazzaroni, A. Matera, A. Marella, A. Maeda, G. Castellano, A. Marchetti, S. Fabris, S. Pioggia, I. Silvestris, D. Ronchetti, S. Lonati, G. Fabbiano, V. Traini, E. Taiana, L. Porretti, F. Colombo, C. De Magistris, M. Scopetti, M. Barbieri, L. Pettine, F. Torricelli, A. Neri, F. Passamonti, M. Lionetti, M.C. Da Vià, N. Bolli
Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins
2023 E. Taiana, C. Bandini, V.K. Favasuli, D. Ronchetti, I. Silvestris, N. Puccio, K. Todoerti, S. Erratico, D. Giannandrea, N. Bolli, N. Amodio, A. Ciarrocchi, R. Chiaramonte, Y. Torrente, R. Piva, A. Neri
The Potential of JAG Ligands as Therapeutic Targets and Predictive Biomarkers in Multiple Myeloma
2023 N. Platonova, E. Lazzari, M. Colombo, M. Falleni, D. Tosi, D. Giannandrea, V. Citro, L. Casati, D. Ronchetti, N. Bolli, A. Neri, F. Torricelli, L.A. Crews, C.H.M. Jamieson, R. Chiaramonte
Expression levels of NONO, a nuclear protein primarily involved in paraspeckles function, are associated with several deregulated molecular pathways and poor clinical outcome in multiple myeloma
2022 D. Ronchetti, V.K. Favasuli, I. Silvestris, K. Todoerti, F. Torricelli, N. Bolli, A. Ciarrocchi, E. Taiana, A. Neri
In Vitro Silencing of lncRNAs Using LNA GapmeRs
2021 E. Taiana, V. Favasuli, D. Ronchetti, E. Morelli, P. Tassone, G. Viglietto, N.C. Munshi, A. Neri, N. Amodio
Epigenetic Regulation of Mitochondrial Quality Control Genes in Multiple Myeloma: A Sequenom MassARRAY Pilot Investigation on HMCLs
2021 P. D'Aquila, D. Ronchetti, M.E. Gallo Cantafio, K. Todoerti, E. Taiana, F. Fabiani, A. Montesanto, A. Neri, G. Passarino, G. Viglietto, D. Bellizzi, N. Amodio