Sfoglia per Autore
Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State
2019 L. Visconti, F. Malagrinò, L. Broggini, C.R. De Luca, F. Moda, S. Gianni, S. Ricagno, A. Toto
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity
2020 A. Achour, L. Broggini, X. Han, R. Sun, C. Santambrogio, J. Buratto, C. Visentin, A. Barbiroli, C.M.G. De Luca, P. Sormanni, F. Moda, A. De Simone, T. Sandalova, R. Grandori, C. Camilloni, S. Ricagno
Glycosylation Tunes Neuroserpin Physiological and Pathological Properties
2020 C. Visentin, L. Broggini, B.M. Sala, R. Russo, A. Barbiroli, C. Santambrogio, S. Nonnis, A. Dubnovitsky, M. Bolognesi, E. Miranda, A. Achour, S. Ricagno
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
2020 C. Visentin, L. Musso, L. Broggini, F. Bonato, R. Russo, C. Moriconi, M. Bolognesi, E. Miranda, S. Dallavalle, D. Passarella, S. Ricagno
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression
2021 D. Hofbauer, D. Mougiakakos, L. Broggini, M. Zaiss, M. Büttner-Herold, C. Bach, B. Spriewald, F. Neumann, S. Bisht, J. Nolting, R. Zeiser, S. Hamarsheh, M. Eberhardt, J. Vera, C. Visentin, C.M.G. De Luca, F. Moda, S. Haskamp, C. Flamann, M. Böttcher, K. Bitterer, S. Völkl, A. Mackensen, S. Ricagno, H. Bruns
MOLECULAR DETERMINANTS UNDERLYING PROTEIN MISFOLDING AND AGGREGATION
2021 L. Broggini
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution
2022 E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Bacic Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni
Multi-{eGO}: an in-silico lens to look into protein aggregation kinetics at atomic resolution
2022 E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Ba( (c))i('(c)) Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni
L- to D-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics
2022 F. Ballabio, L. Broggini, C. Paissoni, X. Han, K. Peqini, B.M. Sala, R. Sun, T. Sandalova, A. Barbiroli, A. Achour, S. Pellegrino, S. Ricagno, C. Camilloni
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024 M. Alberti, G. Poli, L. Broggini, S. Sainas, M. Rizzi, D. Boschi, D.M. Ferraris, E. Martino, S. Ricagno, T. Tuccinardi, M.L. Lolli, R. Miggiano
Untwisted amyloid fibrils from a transgenic mouse model of AL amyloidosis
2025 L. Broggini, D. Bonnet, K.W. Swiderska, S. Bender, G.R. Codo, A. Lampis, G. Martinez-Rivas, P. Duchatelet, A. Danigo, A. Chaves-Sanjuan, C. Sirac, S. Ricagno
The critical role of the variable domain in driving proteotoxicity and aggregation in full-length light chains
2025 S. Puri, A. Gadda, I. Polsinelli, M.M. Barzago, A. Toto, M.K. Sriramoju, C. Visentin, L. Broggini, D.M. Valérie Bonnet, R. Russo, A. Chaves-Sanjuan, G. Merlini, M. Nuvolone, G. Palladini, S. Gianni, S.D. Hsu, L. Diomede, S. Ricagno
A conformational fingerprint for amyloidogenic light chains
2025 C. Paissoni, S. Puri, L. Broggini, M.K. Sriramoju, M. Maritan, R. Russo, V. Speranzini, F. Ballabio, M. Nuvolone, G. Merlini, G. Palladini, S.-.D. Hsu, S. Ricagno, C. Camilloni
Structural characterization of atrial natriuretic peptide amyloid fibrils from patients with atrial fibrillation
2025 L. Broggini, M. Piccoli, A. Chaves-Sanjuan, D.M.V. Bonnet, F. Cirillo, C. Visentin, F. Sonzini, P. Signorelli, I. Lavota, M. Milazzo, S. Nonnis, L. Menicanti, G. Ciconte, C. Pappone, L. Anastasia, S. Ricagno
Biophysical Signatures of IGLV1-44 Light Chains in AL, POEMS, and MM: Uncovering Pathogenic Determinants
2026 D. Pignatelli, F. Sonzini, L. Broggini, M. Nuvolone, R. Paola, P. Giovanni, S. Ricagno
Biophysical Signatures of IGLV1-44 Light Chains in AL, POEMS, and MM: Uncovering Pathogenic Determinants
2026 D. Pignatelli, F. Sonzini, L. Broggini, P. Nuvolone, R. Paola, G. Palladini, S. Ricagno
Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner
2026 M. Mosconi, C. Leonardi, Z. Armour-Garb, B. Rocutto, M. Beeg, G. Meisl, L. Ortigosa-Pascual, L. Broggini, M. Salmona, S. Ricagno, T.P.J. Knowles, L. Diomede
The roles of microenvironment and of an overloaded secretory pathway on amyloid aggregation: updates from ex vivo Cryo EM
2026 L. Broggini, M. Milazzo, T. Schulte, G. Mazzini, S. Caminito, P. Milani, S. Ferro, F. Ferri, D. Marie Valérie Bonnet, S. Nonnis, R. Fernández-Busnadiego, M. Nuvolone, E. Zini, G. Palladini, S. Ricagno
Multifaceted effects of N-glycosylation on amyloidogenic κ light chains in AL amyloidosis
2026 S. Sarita, V. Speranzini, M. Russo, A. Nevone, U. Petralia, M.K. Sriramoju, Y. Wang, L. Broggini, G. Palladini, G. Merlini, M. Nuvolone, S.D. Hsu, S. Ricagno
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