Desmodium adscendens (Sw.) DC. is a plant of the Fabaceae family especially rich in flavonoids but also in alkaloids, terpenoids, steroids, phenols, phenylpropanoids, glycosides, and volatiles. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for the treatment of diarrheas, fever, epilepsy, asthma, leishmaniasis, gastroduodenal ulcer, diabetes, hepatic diseases, etc.). Given the wide uses of D. adscendens, this review summarizes all recent data on D. adscendens evaluating its phytochemistry as well as its ethno-traditional and pharmacological properties. In addition, an association between the phytocompounds of this plant and its potential mechanism of action in cell and animal models has been investigated, focusing with a special emphasis on human experiments.

Desmodium adscendens(Sw.) DC.: A magnificent plant with biological and pharmacological properties / M. Giulia Manzione, J. Herrera-Bravo, J. Sharifi-Rad, D. Kregiel, M. Sevindik, E. Sevindik, Z. Salamoglu, W. Zam, S. Vitalini, C. Hano, W. Kukula-Koch, W. Koch, R. Pezzani. - In: FOOD FRONTIERS. - ISSN 2643-8429. - 3:4(2022 Dec), pp. 677-688. [10.1002/fft2.170]

Desmodium adscendens(Sw.) DC.: A magnificent plant with biological and pharmacological properties

S. Vitalini
Co-ultimo
;
2022

Abstract

Desmodium adscendens (Sw.) DC. is a plant of the Fabaceae family especially rich in flavonoids but also in alkaloids, terpenoids, steroids, phenols, phenylpropanoids, glycosides, and volatiles. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for the treatment of diarrheas, fever, epilepsy, asthma, leishmaniasis, gastroduodenal ulcer, diabetes, hepatic diseases, etc.). Given the wide uses of D. adscendens, this review summarizes all recent data on D. adscendens evaluating its phytochemistry as well as its ethno-traditional and pharmacological properties. In addition, an association between the phytocompounds of this plant and its potential mechanism of action in cell and animal models has been investigated, focusing with a special emphasis on human experiments.
clinical trial; Desmodium adscendens; pharmacological properties; phytochemistry; preclinical studies;
Settore BIO/15 - Biologia Farmaceutica
dic-2022
27-lug-2022
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/961539
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