Lamin proteins not only form the nuclear lamina, but some are also found in the nuclear interior. In this issue of Developmental Cell, Ikegami et al. describe that phosphorylated Lamin C in the nuclear interior interacts with enhancer-like elements and link this to deregulated transcription in progeria.
Phosphorylated Lamins in Euchromatin: New Clues to Progeria / S.G. Manzo, B. van Steensel. - In: DEVELOPMENTAL CELL. - ISSN 1534-5807. - 52:6(2020 Mar 23), pp. 676-678. [10.1016/j.devcel.2020.03.003]
Phosphorylated Lamins in Euchromatin: New Clues to Progeria
S.G. Manzo
Primo
;
2020
Abstract
Lamin proteins not only form the nuclear lamina, but some are also found in the nuclear interior. In this issue of Developmental Cell, Ikegami et al. describe that phosphorylated Lamin C in the nuclear interior interacts with enhancer-like elements and link this to deregulated transcription in progeria.
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