Taking inspiration from the Ctr-1 Mets7 Cu(I) binding motif, effective hybrid catalysts have been developed for asymmetric Henry condensations under green conditions. The introduction of an unnatural dipeptide mimic allowed to increase the catalytic performance. Metal transporters' binding domains could be exploited as a strategy for designing hybrid catalysts for homogeneous catalysis.

Ctr-1 Mets7 motif inspiring new peptide ligands for Cu(i)-catalyzed asymmetric Henry reactions under green conditions / S. Pellegrino, G. Facchetti, A. Contini, M.L. Gelmi, E. Erba, R. Gandolfi, I. Rimoldi. - In: RSC ADVANCES. - ISSN 2046-2069. - 6:75(2016 Jul 20), pp. 71529-71533. [10.1039/c6ra16255j]

Ctr-1 Mets7 motif inspiring new peptide ligands for Cu(i)-catalyzed asymmetric Henry reactions under green conditions

S. Pellegrino
Primo
;
G. Facchetti
Secondo
;
A. Contini;M.L. Gelmi;E. Erba;R. Gandolfi
Penultimo
;
I. Rimoldi
Ultimo
2016

Abstract

Taking inspiration from the Ctr-1 Mets7 Cu(I) binding motif, effective hybrid catalysts have been developed for asymmetric Henry condensations under green conditions. The introduction of an unnatural dipeptide mimic allowed to increase the catalytic performance. Metal transporters' binding domains could be exploited as a strategy for designing hybrid catalysts for homogeneous catalysis.
Settore CHIM/03 - Chimica Generale e Inorganica
Settore CHIM/06 - Chimica Organica
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Descrizione: Ctr-1 Mets7 motif inspiring new peptide ligands for Cu(I)- catalyzed asymmetric Henry reaction under green conditions
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/946313
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