SIRT5 is a member of the Sirtuin family, a class of deacetylating enzymes consisting of seven isoforms, involved in the regulation of several processes, including gene expression, metabolism, stress response, and aging. Considering that the anomalous activity of SIRT5 is linked to many pathological conditions, we present herein an overview of the most interesting modulators, with the aim of contributing to further development in this field.
Insights on the Modulation of SIRT5 Activity: A Challenging Balance / M. Mori, G. Cazzaniga, F. Meneghetti, S. Villa, A. Gelain. - In: MOLECULES. - ISSN 1420-3049. - 27:14(2022 Jul 12), pp. 4449.1-4449.17. [10.3390/molecules27144449]
Insights on the Modulation of SIRT5 Activity: A Challenging Balance
M. MoriPrimo
;G. CazzanigaSecondo
;F. Meneghetti;S. Villa
Penultimo
;A. GelainUltimo
2022
Abstract
SIRT5 is a member of the Sirtuin family, a class of deacetylating enzymes consisting of seven isoforms, involved in the regulation of several processes, including gene expression, metabolism, stress response, and aging. Considering that the anomalous activity of SIRT5 is linked to many pathological conditions, we present herein an overview of the most interesting modulators, with the aim of contributing to further development in this field.
| File | Dimensione | Formato | |
|---|---|---|---|
|
molecules-27-04449.pdf
accesso aperto
Tipologia:
Publisher's version/PDF
Dimensione
3.37 MB
Formato
Adobe PDF
|
3.37 MB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
