A long period of isolation was observed in patients hospitalized for COVID-19 in Milan over March-September 2020 (45; IQR: 37–54 days). A significantly shorter period would have been observed by the application of May-WHO (22, IQR: 17–30 days, P < 0.001) and October-Italian (26, IQR: 21–34 days, P < 0.001) Guidelines. The adoption of the new symptom-based criteria is likely to lead to a significant reduction in the length of the isolation period with potential social, economic and psychological benefits, particularly in the younger population with mild/moderate disease and no comorbidities. In our opinion, the release from isolation after 21 days from symptoms onset, even without a PCR diagnostic test, in most cases seems the most adequate strategy that could balance precautions to prevent SARS CoV-2 transmission and unnecessary prolonged isolation or overuse of diagnostic testing.

A Quantitative Estimate of the Expected Shortening of the Median Isolation Period of Patients With COVID-19 After the Adoption of a Symptom-Based Strategy / F. Bai, A. Tavelli, G. Mule, C. Falcinella, D. Mondatore, D. Tesoro, D. Barbanotti, D. Tomasoni, R. Castoldi, M. Augello, M. Allegrini, G. Tagliaferri, A. Cona, A. Cozzi-Lepri, G. Marchetti, A. d'Arminio Monforte. - In: FRONTIERS IN PUBLIC HEALTH. - ISSN 2296-2565. - 9(2021), pp. 639347.1-639347.7. [10.3389/fpubh.2021.639347]

A Quantitative Estimate of the Expected Shortening of the Median Isolation Period of Patients With COVID-19 After the Adoption of a Symptom-Based Strategy

F. Bai
Primo
;
C. Falcinella;D. Mondatore;D. Tesoro;D. Barbanotti;M. Augello;M. Allegrini;G. Tagliaferri;A. Cona;A. d'Arminio Monforte
Ultimo
2021

Abstract

A long period of isolation was observed in patients hospitalized for COVID-19 in Milan over March-September 2020 (45; IQR: 37–54 days). A significantly shorter period would have been observed by the application of May-WHO (22, IQR: 17–30 days, P < 0.001) and October-Italian (26, IQR: 21–34 days, P < 0.001) Guidelines. The adoption of the new symptom-based criteria is likely to lead to a significant reduction in the length of the isolation period with potential social, economic and psychological benefits, particularly in the younger population with mild/moderate disease and no comorbidities. In our opinion, the release from isolation after 21 days from symptoms onset, even without a PCR diagnostic test, in most cases seems the most adequate strategy that could balance precautions to prevent SARS CoV-2 transmission and unnecessary prolonged isolation or overuse of diagnostic testing.
COVID-19; criteria for releasing COVID-19 patients from isolation; isolation and quarantine; molecular diagnosis; SARS CoV-2
Settore MED/17 - Malattie Infettive
10-giu-2021
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/897929
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