Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells (Rauh et al., 2005 [this issue of Immunity]). Copyright
Macrophage polarization comes of age / A. Mantovani, A. Sica, M. Locati. - In: IMMUNITY. - ISSN 1074-7613. - 23:4(2005), pp. 344-346.
Macrophage polarization comes of age
A. MantovaniPrimo
;M. LocatiUltimo
2005
Abstract
Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells (Rauh et al., 2005 [this issue of Immunity]). Copyright
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