Stilbenoids (resveratrol and its derivatives) are secondary metabolites produced by plants as defence mechanism to microbial infection. These compounds are known for their anti-inflammatory action and health benefits in preventing a wide range of disorders (e.g. cancer and cardiovascular diseases). However, their antimicrobial properties are less investigated. A series of 8 stilbenoid compounds were synthesized and their antifungal activity against 19 wild strains of filamentous fungi and yeasts (isolated from the environment and food) was tested in vitro. Using an agar diffusion assay, compounds were tested at the concentration of 100 μg/ml on filamentous fungi and yeasts at 104 CFU/ml. The results showed that tested derivatives possess moderate antifungal activity: in particular, monomeric stilbenoids 3’-hydroxy-pterostilbene and piceatannol, and dimeric stilbenoids (±)-trans-δ-viniferin and pallidol were active against mycotoxigenic fungi.
Inhibitory activity of stilbenes against filamentous fungi / L.M. Mattio, G. Catinella, M. Iriti, L. Vallone. - In: ITALIAN JOURNAL OF FOOD SAFETY. - ISSN 2239-7132. - 10:1(2021 Mar), pp. 8461.1-8461.4. ((Intervento presentato al 29. convegno AIVI tenutosi a Bari nel 2019.
|Titolo:||Inhibitory activity of stilbenes against filamentous fungi|
MATTIO, LUCE MICHELA (Primo)
CATINELLA, GIORGIA (Secondo)
IRITI, MARCELLO (Penultimo) [Data Curation]
VALLONE, LISA (Ultimo) [Project Administration] (Corresponding)
|Parole Chiave:||stilbenes; resveratrol; antimicrobial activity; food-borne fungi|
|Settore Scientifico Disciplinare:||Settore VET/04 - Ispezione degli Alimenti di Origine Animale|
|Data di pubblicazione:||mar-2021|
|Enti collegati al convegno:||Associazione Italiana Veterinari Igienisti|
|Data ahead of print / Data di stampa:||feb-2021|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.4081/ijfs.2021.8461|
|Appare nelle tipologie:||01 - Articolo su periodico|