Vitamin D supplementation and cardiac inflammation

Raw data of the clinical trial NCT03403933. We enrolled older adults scheduled for major orthopaedic surgery and suffering from hypovitaminosis D. Patients underwent 6-months calcifediol supplementation after surgery. After the normalization of low levels of vitamin D, we were able to observe a reduction of circulating TNFα and ADMA together with the amelioration of cardiac function. The dataset was used to write the article "Vitamin D, cardio-inflammation, and endothelial dysfunction in older adults after orthopedic surgery: results from an open-label trial to ameliorate cardiac function", which was published by the Journal of Nutrition Clinique et Métabolisme in 2020.