The clinical manifestation of COVID-19 can vary from an asymptomatic course to ARDS requiring invasive mechanical ventilation and extracorporeal membrane oxygenation. A kidney transplanted patient infected with SARS CoV-2 infection showed a mild disease despite immune suppression. It is possible that Immunosuppression can “be protective” as the cytokine storm is an important factor in the disease story. Despite the good outcome reported in the present case report, is remains of vital importance the solid organ transplant patients use precautions in order to avoid the infection.

SARS Cov-2 infection in a renal-transplanted patient: A case report / E. Seminari, M. Colaneri, M. Sambo, I. Gallazzi, A. Di Matteo, S. Roda, R. Bruno, M.U. Mondelli, E. Brunetti, L. Maiocchi, V. Zuccaro, L. Pagnucco, B. Mariani, S. Ludovisi, R. Lissandrin, A. Parisi, P. Sacchi, S.F.A. Patruno, G. Michelone, R. Gulminetti, D. Zanaboni, S. Novati, R. Maserati, P. Orsolini, M. Vecchia, M. Sciarra, E. Asperges, A. Di Filippo, S. Biscarini, M. Lupi, T.C. Pieri, M. Sachs, P. Valsecchi, S. Perlini, C. Alfano, M. Bonzano, F. Briganti, G. Crescenzi, A.G. Falchi, R. Guarnone, B. Guglielmana, E. Maggi, I. Martino, P. Pettenazza, S. Pioli di Marco, F. Quaglia, A. Sabena, F. Salinaro, F. Speciale, I. Zunino, M. De Lorenzo, G. Secco, L. Dimitry, G. Cappa, I. Maisak, B. Chiodi, M. Sciarrini, B. Barcella, F. Resta, L. Moroni, G. Vezzoni, L. Scattaglia, E. Boscolo, C. Zattera, T.M. Fidel, C. Vincenzo, D. Vignaroli, M. Bazzini, G. Iotti, F. Mojoli, M. Belliato, L. Perotti, S. Mongodi, G. Tavazzi, G. Marseglia, A. Licari, I. Brambilla, B. Daniela, B. Antonella, C. Patrizia, C. Giulia, C. Giuditta, C. Marta, D. Rossana, F. Milena, M. Bianca, M. Roberta, E. Milioni, P. Stefania, P. Maurizio, P. Elena, P. Antonio, R. Francesca, S. Antonella, Z. Maurizio, A. Guy, B. Laura, C. Ermanna, C. Giuliana, D. Luca, F. Gabriella, G. Cartago Scattaglia, G. Alessia, L. Viviana, L. Claudia, M. Valentina, P. Simona, P. Marta, B. Alice, C. Giacomo, C. Irene, C. Alfonso, R. Di Martino, A. Di Napoli, F. Alessandro, F. Guglielmo, F. Loretta, G. Federica, M. Alessandra, N. Federica, R. Giacomo, R. Beatrice, S.I. Maria, T. Monica, V.N. Edoardo, A. Cerino, S. Varchetta, B. Oliviero, S. Mantovani, D. Mele, M. Calvi, M. Tizzonis, C. Nicora, A. Triarico, V. Petronella, C. Marena, A. Muzzi, P. Lago, F. Comandatore, G. Bissignandi, S. Gaiarsa, M. Rettani, C. Band. - In: AMERICAN JOURNAL OF TRANSPLANTATION. - ISSN 1600-6135. - (2020). [Epub ahead of print] [10.1111/ajt.15902]

SARS Cov-2 infection in a renal-transplanted patient: A case report

L. Maiocchi;V. Zuccaro;B. Mariani;A. Di Filippo;P. Valsecchi;S. Perlini;I. Martino;G. Cappa;M. Sciarrini;B. Barcella;L. Moroni;L. Perotti;A. Licari;M. Bianca;E. Milioni;L. Viviana;P. Marta;F. Guglielmo;M. Alessandra;F. Comandatore;S. Gaiarsa;
2020

Abstract

The clinical manifestation of COVID-19 can vary from an asymptomatic course to ARDS requiring invasive mechanical ventilation and extracorporeal membrane oxygenation. A kidney transplanted patient infected with SARS CoV-2 infection showed a mild disease despite immune suppression. It is possible that Immunosuppression can “be protective” as the cytokine storm is an important factor in the disease story. Despite the good outcome reported in the present case report, is remains of vital importance the solid organ transplant patients use precautions in order to avoid the infection.
clinical research/practice; immunosuppressant – calcineurin inhibitor: tacrolimus; infection and infectious agents – viral; infectious disease
Settore MED/07 - Microbiologia e Microbiologia Clinica
Settore MED/17 - Malattie Infettive
apr-2020
Article (author)
File in questo prodotto:
File Dimensione Formato  
ajt.15902.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 254.75 kB
Formato Adobe PDF
254.75 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/745369
Citazioni
  • ???jsp.display-item.citation.pmc??? 39
  • Scopus 70
  • ???jsp.display-item.citation.isi??? 64
social impact