Tuberculosis (TB) is one of the commonest infectious diseases in the world with 10.4 million new cases estimated in 2015, of which one million are children. The prevalence of active TB in pregnant and postpartum women from high-prevalence countries is higher than 60 cases per 100 000 people per year. Here we presented three different cases of infants born to mothers with active TB and we reviewed the current recommendations on the prophylaxis of neonatal and perinatal tuberculosis. Currently there is a lack of concordance regarding the most appropriate time for TB reassessment and discontinuation of prophylaxis after birth. More reliable diagnostic tests are still needed to help physicians to decide the appropriate time to safely discontinue prophylaxis. An uniform consensus on management of infants born to TBCinfected mothers is highly necessary to improve the measures and interventions to limit the infection at birth.

Management of newborns at risk of neonatal and perinatal tuberculosis / V. Giacomet, L. Cococcioni, S. Pisanelli, A.R. Benincaso, P. Nannini, T. Genoni, G.V. Zuccotti. - In: ASIAN PACIFIC JOURNAL OF TROPICAL DISEASE. - ISSN 2222-1808. - 7:9(2017), pp. 569-571.

Management of newborns at risk of neonatal and perinatal tuberculosis

V. Giacomet;L. Cococcioni;S. Pisanelli;A.R. Benincaso;P. Nannini;T. Genoni;G.V. Zuccotti
2017

Abstract

Tuberculosis (TB) is one of the commonest infectious diseases in the world with 10.4 million new cases estimated in 2015, of which one million are children. The prevalence of active TB in pregnant and postpartum women from high-prevalence countries is higher than 60 cases per 100 000 people per year. Here we presented three different cases of infants born to mothers with active TB and we reviewed the current recommendations on the prophylaxis of neonatal and perinatal tuberculosis. Currently there is a lack of concordance regarding the most appropriate time for TB reassessment and discontinuation of prophylaxis after birth. More reliable diagnostic tests are still needed to help physicians to decide the appropriate time to safely discontinue prophylaxis. An uniform consensus on management of infants born to TBCinfected mothers is highly necessary to improve the measures and interventions to limit the infection at birth.
Neonatal tuberculosis; Perinatal tuberculosis; Pregnancy; Tuberculosis
Settore MED/38 - Pediatria Generale e Specialistica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/728851
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