Second-messenger effectors (ThromboSol(R)), together with low-dose dimethyl sulfoxide (DMSO) (2%), are described as a new cryopreservation solution. The solution allows high yield recovery of cryopreserved platelets with a residual platelet function equal or superior to that of 6% DMSO-cryopreserved platelets. The hemostatic function of cryopreserved platelets was measured by PFA-100(TM).
Platelet cryopreservation using second-messenger effector and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer / P. Borzini, A. Lazzaro, L. Mazzucco, R. Schiavo, J. Connor, S. Siena. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 85:8(2000 Aug), pp. 885-887.
Platelet cryopreservation using second-messenger effector and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer
S. Siena
2000
Abstract
Second-messenger effectors (ThromboSol(R)), together with low-dose dimethyl sulfoxide (DMSO) (2%), are described as a new cryopreservation solution. The solution allows high yield recovery of cryopreserved platelets with a residual platelet function equal or superior to that of 6% DMSO-cryopreserved platelets. The hemostatic function of cryopreserved platelets was measured by PFA-100(TM).
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