Objectives: The validity of lung ultrasound (LUS) in the diagnosis of interstitial or focal lung pathologies is well documented, we assessed its accuracy in the diagnosis of pulmonary tuberculosis (PTB). Methods: Sonographic signs suggestive of PTB and their diagnostic accuracy were evaluated in patients admitted with clinical suspicion of PTB. Consolidations, subpleural nodules, pleural thickenings or irregularities and pleural effusion were assessed. LUS signs significantly associated with PTB in the univariate analysis (p < .05) were entered in a multivariate logistic regression model. Results: PTB was confirmed in 51 out of 102 patients. Multiple consolidations (OR 3.54, 95%CI 1.43–8.78), apical consolidations (OR 9.65, 95%CI 3.02–30.78), superior quadrant consolidations (OR 4.01, 95%CI 1.76–9.14), and subpleural nodules (OR 5.29, 95%CI 2.27–12.33) were significantly associated with PTB diagnosis. Apical consolidation (OR 9.67, 95%CI 2.81–33.25, p 0.003) and subpleural nodules (OR 5.30, 95%CI 2.08–13.52, p 0.005) retained a significant association in a multivariate model, with an overall accuracy of 0.799. Conclusions: Our data suggest a possible role of LUS in the diagnosis of PTB, a high burden pathological condition for which the delay in diagnosis still represents a critical point in the control of the disease.
Lung ultrasonography in pulmonary tuberculosis : a pilot study on diagnostic accuracy in a high-risk population / M. Montuori, F. Casella, G. Casazza, F. Franzetti, P. Pini, C. Invernizzi, D. Torzillo, G. Rizzardini, M. Galli, C. Cogliati. - In: EUROPEAN JOURNAL OF INTERNAL MEDICINE. - ISSN 0953-6205. - 66(2019 Aug), pp. 29-34.
|Titolo:||Lung ultrasonography in pulmonary tuberculosis : a pilot study on diagnostic accuracy in a high-risk population|
|Parole Chiave:||Diagnostic imaging; Lung ultrasonography; Pulmonary tuberculosis|
|Settore Scientifico Disciplinare:||Settore MED/01 - Statistica Medica|
Settore MED/09 - Medicina Interna
Settore MED/17 - Malattie Infettive
|Data di pubblicazione:||ago-2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.ejim.2019.06.002|
|Appare nelle tipologie:||01 - Articolo su periodico|
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