The purpose of the present work is to evaluate the efficacy of an approach that combines clinical history, skin tests results, and premedication, in preventing recurrent hypersensitivity reactions to iodinated contrast media (ICM). Skin Prick tests, Intradermal tests, and Patch tests were performed in 36 patients with a previous reaction to ICM. All patients underwent a second contrast enhanced radiological procedure with an alternative ICM selected on the basis of the proposed approach. After alternative ICM re-injection, only one patient presented a mild NIR. The proposed algorithm, validated in clinical settings where repeated radiological exams are needed, offers a safe and practical approach for protecting patients from recurrent hypersensitivity reactions to ICM.

Proposal of a skin tests based approach for the prevention of recurrent hypersensitivity reactions to iodinated contrast media / E. Della-Torre, A. Berti, M.R. Yacoub, B. Guglielmi, E. Tombetti, M.G. Sabbadini, S. Voltolini, G. Colombo. - In: EUROPEAN ANNALS OF ALLERGY AND CLINICAL IMMUNOLOGY. - ISSN 1764-1489. - 47:3(2015), pp. 77-85.

Proposal of a skin tests based approach for the prevention of recurrent hypersensitivity reactions to iodinated contrast media

E. Tombetti;M.G. Sabbadini;
2015

Abstract

The purpose of the present work is to evaluate the efficacy of an approach that combines clinical history, skin tests results, and premedication, in preventing recurrent hypersensitivity reactions to iodinated contrast media (ICM). Skin Prick tests, Intradermal tests, and Patch tests were performed in 36 patients with a previous reaction to ICM. All patients underwent a second contrast enhanced radiological procedure with an alternative ICM selected on the basis of the proposed approach. After alternative ICM re-injection, only one patient presented a mild NIR. The proposed algorithm, validated in clinical settings where repeated radiological exams are needed, offers a safe and practical approach for protecting patients from recurrent hypersensitivity reactions to ICM.
'Premedication; Hypersensitivity; Iodinated contrast media; Reactions; Skin tests; Immunology and Allergy
Settore MED/09 - Medicina Interna
http://www.eurannallergyimm.com/cont/journals-articles/366/volume-proposal-skin-tests-based-approach-971allasp1.pdf
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/646533
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