A new study has identified novel genes involved in sporadic frontotemporal lobar degeneration with neuronal inclusions of TAR DNA-binding protein 43. These findings might enable the elucidation of pathogenic mechanisms of the disease and have implications for the identification of potential therapeutic targets.
Genetic risk factors and role of immune dysfunction in FTLD / D. Galimberti. - In: NATURE REVIEWS. NEUROLOGY. - ISSN 1759-4758. - 15:5(2019 May 01), pp. 250-251.
Genetic risk factors and role of immune dysfunction in FTLD
D. Galimberti
2019
Abstract
A new study has identified novel genes involved in sporadic frontotemporal lobar degeneration with neuronal inclusions of TAR DNA-binding protein 43. These findings might enable the elucidation of pathogenic mechanisms of the disease and have implications for the identification of potential therapeutic targets.
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