A host of clinical scenarios can be depicted in hereditary autoinflammatory diseases, and the cardiovascular system can also be involved especially in familial Mediterranean fever (FMF), caused by mutations in the MEFV gene, and tumour necrosis factor receptor-associated periodic syndrome (TRAPS), caused by mutations in the TNFRSF1A gene. Pericardial diseases are the most represented cardiovascular abnormalities, though the role of MEFV and TNFRSF1A in the initiation of heart involvement has not been demonstrated formally and will be discussed herein.

Autoinflammatory diseases and cardiovascular manifestations / D. Rigante, L. Cantarini, M. Imazio, O.M. Lucherini, E. Sacco, M. Galeazzi, M.G. Brizi, A. Brucato. - In: ANNALS OF MEDICINE. - ISSN 0785-3890. - 43:5(2011), pp. 341-346.

Autoinflammatory diseases and cardiovascular manifestations

A. Brucato
2011

Abstract

A host of clinical scenarios can be depicted in hereditary autoinflammatory diseases, and the cardiovascular system can also be involved especially in familial Mediterranean fever (FMF), caused by mutations in the MEFV gene, and tumour necrosis factor receptor-associated periodic syndrome (TRAPS), caused by mutations in the TNFRSF1A gene. Pericardial diseases are the most represented cardiovascular abnormalities, though the role of MEFV and TNFRSF1A in the initiation of heart involvement has not been demonstrated formally and will be discussed herein.
Autoinflammatory diseases; cardiovascular abnormalities; familial Mediterranean fever; tumour necrosis factor receptor-associated periodic syndrome
Settore MED/09 - Medicina Interna
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/635121
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