Intestinal metaplasia (IM) is defined as the replacement of gastric mucous cells with an epithelium similar to that of the small intestine. The purpose of this retrospective study is to evaluate presence, type of gastric IM and possible association with carcinoma in histologic examinations of endoscopic gastric biopsy specimens obtained from 170 dogs and 50 cats. IM was found in 28 dogs (16,5%) and 5 cats (10%). Gastric carcinoma was associated with IM in four dogs and one cat. In 2 dogs repeated endoscopy with biopsy sampling showed progression of IM towards carcinoma in one case and complete regression in the other case. The understanding of the role of IM in gastric carcinogenesis in small animals needs further studies. Nonetheless, the results obtained suggest the necessity of endoscopic and histologic re-evaluation of patients with gastric IM.
|Titolo:||Gastric Intestinal metaplasia in the dog and cat : a retrospective study of 33 cases (January 2003-December 2006)|
|Autori interni:||GUALTIERI, MASSIMO (Ultimo)|
COCCI, ANDREA (Primo)
MONTI, SIMONE (Penultimo)
|Parole Chiave:||gastric intestinal metaplasia ; premalignant gastric lesions ; carcinoma|
|Settore Scientifico Disciplinare:||Settore VET/09 - Clinica Chirurgica Veterinaria|
|Data di pubblicazione:||2008|
|Enti collegati al convegno:||British Small Animal Veterinary Association|
|Tipologia:||Book Part (author)|
|Appare nelle tipologie:||03 - Contributo in volume|
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