This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
Microbiological testing of adults hospitalised with community-acquired pneumonia : an international study / M. Carugati, S. Aliberti, L.F. Reyes, R.F. Sadud, M. Irfan, C. Prat, N.J. Soni, P. Faverio, A. Gori, F. Blasi, M.I. Restrepo. - In: ERJ OPEN RESEARCH. - ISSN 2312-0541. - 4:4(2018), pp. 00096-2018.1-00096-2018.13.
|Titolo:||Microbiological testing of adults hospitalised with community-acquired pneumonia : an international study|
ALIBERTI, STEFANO (Co-primo) (Corresponding)
BLASI, FRANCESCO BRUNO ARTURO (Penultimo)
|Settore Scientifico Disciplinare:||Settore MED/10 - Malattie dell'Apparato Respiratorio|
|Data di pubblicazione:||2018|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1183/23120541.00096-2018|
|Appare nelle tipologie:||01 - Articolo su periodico|
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