In this data article, HPLC analyses were applied to investigate the hydrolytic and thermal stability of domiphen bromide a FDA approved OTC ingredients endowed with antimicrobial activity. The data obtained by stressing domiphen bromide in acid, base and thermal conditions enlarge the research article published by Fumagalli et al. [2]. The chromatograms herein presented reveal that domiphen bromide is stable under acidic and thermal stress while the treatment with base yield to a by-product. The para-bromo derivative, p-bromodomiphen bromide shows the same behavior under the up mentioned stressed conditions.

Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide / L. Fumagalli, A. Moretto, E. Gilardoni, C. Picozzi, G. Vistoli, M. Carini. - In: DATA IN BRIEF. - ISSN 2352-3409. - 20(2018 Oct), pp. 1363-1366. [10.1016/j.dib.2018.08.152]

Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide

L. Fumagalli
Primo
Conceptualization
;
E. Gilardoni
Investigation
;
C. Picozzi
Data Curation
;
G. Vistoli
Supervision
;
M. Carini
Ultimo
Data Curation
2018

Abstract

In this data article, HPLC analyses were applied to investigate the hydrolytic and thermal stability of domiphen bromide a FDA approved OTC ingredients endowed with antimicrobial activity. The data obtained by stressing domiphen bromide in acid, base and thermal conditions enlarge the research article published by Fumagalli et al. [2]. The chromatograms herein presented reveal that domiphen bromide is stable under acidic and thermal stress while the treatment with base yield to a by-product. The para-bromo derivative, p-bromodomiphen bromide shows the same behavior under the up mentioned stressed conditions.
Multidisciplinary
Settore CHIM/08 - Chimica Farmaceutica
ott-2018
ago-2018
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/594967
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