The formation of a new volatile derivative of muramic acid is described. The procedure entails a reaction with O-(pentafluorobenzyl)hydroxylamine in pyridine to give the corresponding oxime and a treatment with acetic anhydride in the presence of 4-NJ+‘-dimethylaminopyridine. The structures of the obtained derivatives have been confirmed by MS. The influence of various catalyst amounts used during the acetylation step was studied and a mechanism was proposed in order to explain the different reaction courses.
New, stable halogenated derivative suitable for the gas chromatographic determination of muramic acid [short communication] / P.A. Biondi, L.M. Chiesa, C. Mariani, P. Renon. - In: JOURNAL OF CHROMATOGRAPHY A. - ISSN 0021-9673. - 726:1/2(1996 Mar), pp. 246-252.
New, stable halogenated derivative suitable for the gas chromatographic determination of muramic acid [short communication]
P.A. Biondi;L.M. Chiesa;C. Mariani;P. Renon
1996
Abstract
The formation of a new volatile derivative of muramic acid is described. The procedure entails a reaction with O-(pentafluorobenzyl)hydroxylamine in pyridine to give the corresponding oxime and a treatment with acetic anhydride in the presence of 4-NJ+‘-dimethylaminopyridine. The structures of the obtained derivatives have been confirmed by MS. The influence of various catalyst amounts used during the acetylation step was studied and a mechanism was proposed in order to explain the different reaction courses.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
