In this study memory for public events was evaluated in 15 amnesic mild cognitive impairment (aMCI) patients, whose clinical diagnosis was refined through a stringent selection procedure. A total of 9 patients were longitudinally reassessed over an 18-month period. About half of the participants were impaired at baseline and nearly 80% at the end of the 18-month follow-up. Moreover, retrograde memory declined significantly over time. Evidence of a pathological Ribot-type temporal gradient was found in about half of the aMCI patients. This is the first report of a remote memory deficit in aMCI. It highlights amnesia for public events as a frequent accompaniment of this condition. The findings tie in with the hypothesized role of the hippocampal complex in long-term memory.
|Titolo:||Mild Cognitive Impairment does entail retrograde amnesia for pubblic events|
SAETTI, MARIA CRISTINA (Penultimo)
SPINNLER, HANS RUEDI (Ultimo)
|Settore Scientifico Disciplinare:||Settore MED/26 - Neurologia|
|Data di pubblicazione:||gen-2009|
|Digital Object Identifier (DOI):||10.1080/13803390801978864|
|Appare nelle tipologie:||01 - Articolo su periodico|