Improvements in virological control among women conceiving on combination antiretroviral therapy in Western Europe

Bailey, H.; Townsend, C.L.; Cortina-Borja, M.; Thorne, C.; Giaquinto, C.; Rampon, O.; Mazza, A.; De Rossi, A.; Grosch Wörner, I.; Mok, J.; de José MI,; Larrú Martínez, B.; Peña, J.; Gonzalez Garcia, J.; Arribas Lopez JR,; Garcia Rodriguez MC,; Asensi-Botet, F.; Otero, M.; Pérez-Tamarit, D.; Scherpbier, H.; Kreyenbroek, M.; Godfried, M.; Nellen, F.; Boer, K.; Navér, L.; Bohlin, A.; Lindgren, S.; Kaldma, A.; Belfrage, E.; Levy, J.; Barlow, P.; Manigart, Y.; Hainaut, M.; Goetghebuer, T.; Brichard, B.; De Camps, J.; Thiry, N.; Deboone, G.; Waterloos, H.; Viscoli, C.; De Maria, A.; Bentivoglio, G.; Ferrero, S.; Gotta, C.; Mûr, A.; Payà, A.; López-Vilchez, M.; Carreras, R.; Valerius, H.; Rosenfeldt, V.; Coll, C.; Suy, A.; Perez, J.; Fortuny, C.; Boguña, J.; Savasi, V.; Fiore, S.; Crivelli, M.; Viganò, A.; Giacomet, V.; Cerini, C.; Raimondi, C.; Zuccotti, G.; Alberico, S.; Maso, G.; Airoud, N.; Taylor, G.; Lyall, E.; Penn, Z.; Buffolano, W.; Tiseo, R.; Martinelli, P.; Sansone, M.; Maruotti, G.; Agangi, A.; Tibaldi, C.; Marini, S.; Masuelli, G.; Benedetto, C.; Niemieç, T.; Marczynska, M.; Dobosz, S.; Popielska, J.; Oldakowska, A.

doi:10.1097/QAD.0b013e32836378e4

Among 396 HIV-infected women conceiving on combination antiretroviral therapy and enrolled in the European Collaborative Study in 2000-2011, the proportion with virological failure (>200 copies/ml after ≥ 24 weeks of treatment) declined substantially from 34% in 2000-2001 to 3% in 2010-2011. In adjusted analyses, younger women and those with at least two children were at increased risk of virological failure, highlighting the importance of close monitoring and adherence support.

Improvements in virological control among women conceiving on combination antiretroviral therapy in Western Europe / H. Bailey, C.L. Townsend, M. Cortina-Borja, C. Thorne, C. Giaquinto, O. Rampon, A. Mazza, A. De Rossi, I. Grosch Wörner, J. Mok, M. de José, B. Larrú Martínez, J. Peña, J. Gonzalez Garcia, J. Arribas Lopez, M. Garcia Rodriguez, F. Asensi-Botet, M. Otero, D. Pérez-Tamarit, H. Scherpbier, M. Kreyenbroek, M. Godfried, F. Nellen, K. Boer, L. Navér, A. Bohlin, S. Lindgren, A. Kaldma, E. Belfrage, J. Levy, P. Barlow, Y. Manigart, M. Hainaut, T. Goetghebuer, B. Brichard, J. De Camps, N. Thiry, G. Deboone, H. Waterloos, C. Viscoli, A. De Maria, G. Bentivoglio, S. Ferrero, C. Gotta, A. Mûr, A. Payà, M. López-Vilchez, R. Carreras, H. Valerius, V. Rosenfeldt, C. Coll, A. Suy, J. Perez, C. Fortuny, J. Boguña, V. Savasi, S. Fiore, M. Crivelli, A. Viganò, V. Giacomet, C. Cerini, C. Raimondi, G. Zuccotti, S. Alberico, G. Maso, N. Airoud, G. Taylor, E. Lyall, Z. Penn, W. Buffolano, R. Tiseo, P. Martinelli, M. Sansone, G. Maruotti, A. Agangi, C. Tibaldi, S. Marini, G. Masuelli, C. Benedetto, T. Niemieç, M. Marczynska, S. Dobosz, J. Popielska, A. Oldakowska. - In: AIDS. - ISSN 0269-9370. - 27:14(2013), pp. 2312-2315.