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EnglishThe surgical resection of meningiomas can be complicated by venous thromboembolism (VTE) in the post-operative period, but the exact incidence of this event is not known. Aim of this study was to assess the occurrence of VTE in patients operated for meningioma who underwent a post-operative clinical and objective screening for VTE. Patients undergoing meningioma resection between 2000 and 2010 who accepted to be investigated for VTE in the post-operative period were included in the study. The screening included daily clinical assessment, pulmonary perfusion scintigraphy (Q-SCAN) on day 2 and venous compression ultrasonography (CUS) of the lower limbs within day 7. The univariate and multivariate statistical analysis of risk factors for VTE included sex, age, presence of comorbidities, pre- and post-operative Karnofsky Performance scale (KPS), post-operative neurological worsening and post-operative walking ability. Two-hundred and seventy-five patients were included in the study. VTE was diagnosed in 82 patients (29.8%). Univariate analysis revealed that age ≥ 65 years, cardiovascular comorbidities, pre- and post-operative KPS < 80/100, post-operative neurological worsening and impaired post-operative walking ability were significantly associated with VTE. Multivariate analysis confirmed only age ≥ 65 years (p = 0.011) and post-operative KPS < 80/100 (p = 0.002) as independent risk factors for VTE. Patients operated for meningioma have a 30% risk of VTE. Age ≥ 65 years and post-operative KPS < 80 were independent risk factors for VTE.
Risk of post-operative venous thromboembolism in patients with meningioma / G. Carrabba, M. Riva, V. Conte, A. Di Cristofori, M. Caroli, M. Locatelli, M. Castellani, P. Bucciarelli, A. Artoni, N. Stocchetti, I. Martinelli, P. Rampini. - In: JOURNAL OF NEURO-ONCOLOGY. - ISSN 0167-594X. - 138:2(2018 Jun), pp. 401-406.
| Titolo: | Risk of post-operative venous thromboembolism in patients with meningioma |
| Autori: | |
| Parole Chiave: | Deep vein thrombosis; Meningioma; Pulmonary embolism; Venous thromboembolism |
| Settore Scientifico Disciplinare: | Settore MED/27 - Neurochirurgia Settore MED/41 - Anestesiologia |
| Data di pubblicazione: | giu-2018 |
| Rivista: | |
| Tipologia: | Article (author) |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s11060-018-2810-z |
| Appare nelle tipologie: | 01 - Articolo su periodico |
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