In this systematic review, we will consider and debate studies that have explored the effects of omega-3 polyunsaturated fatty acids (PUFAs) in three major, and somehow related, developmental psychiatric disorders: Autism, Attention Deficit and Hyperactivity disorder and Psychosis. The impact of omega-3 PUFAs on clinical symptoms and, if possible, brain trajectory in children and adolescents suffering from these illnesses will be reviewed and discussed, considering the biological plausibility of the effects of omega-3 fatty acids, together with their potential perspectives in the field. Heterogeneity in study designs will be discussed in the light of differences in results and interpretation of studies carried out so far.

The role of omega-3 fatty acids in developmental psychopathology : A systematic review on early psychosis, autism, and ADHD / C. Agostoni, M. Nobile, V. Ciappolino, G. Delvecchio, A. Tesei, S. Turolo, A. Crippa, A. Mazzocchi, C.A. Altamura, P. Brambilla. - In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. - ISSN 1661-6596. - 18:12(2017 Dec), pp. 2608.1-2608.25.

The role of omega-3 fatty acids in developmental psychopathology : A systematic review on early psychosis, autism, and ADHD

C. Agostoni
Primo
;
G. Delvecchio;A. Mazzocchi;P. Brambilla
Ultimo
2017

Abstract

In this systematic review, we will consider and debate studies that have explored the effects of omega-3 polyunsaturated fatty acids (PUFAs) in three major, and somehow related, developmental psychiatric disorders: Autism, Attention Deficit and Hyperactivity disorder and Psychosis. The impact of omega-3 PUFAs on clinical symptoms and, if possible, brain trajectory in children and adolescents suffering from these illnesses will be reviewed and discussed, considering the biological plausibility of the effects of omega-3 fatty acids, together with their potential perspectives in the field. Heterogeneity in study designs will be discussed in the light of differences in results and interpretation of studies carried out so far.
Attention Deficit Hyperactivity Disorder (ADHD); autism; DocosaHexaenoic acid (DHA); Eicosapentaenoic acid (EPA); first psychotic episode; neurodevelopment; omega-3; PUFAs; ultra-high risk for psychosis; catalysis; molecular biology; spectroscopy; computer science applications1707 computer vision and pattern recognition; physical and theoretical chemistry; organic chemistry; inorganic chemistry
Settore MED/38 - Pediatria Generale e Specialistica
Settore MED/25 - Psichiatria
dic-2017
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/556946
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