The results of this study show that a high percentage of human cord-blood lymphocytes bears receptors for peanut agglutinin. Determination of the presence of other lymphocyte markers (E rosettes, membrane immunoglobulins, alpha-naphthyl-acetate esterase, Ia antigens) in the peanut-positive cells indicated that they include both T and B cells. The peanut receptor, also expressed by blast cells of most acute, but not chronic, leukemias, seems to be a marker of immaturity for both T- and B-lymphocyte subsets in man as it is in the mouse.

Receptors for peanut agglutinin on a high percentage of human cord-blood lymphocytes : phenotype characterization of peanut-positive cells / R. Maccario, F.A. Ferrari, S. Siena, M.A. Vitiello, A. Martini, A.G. Siccardi, A.G. Ugazio. - In: THYMUS. - ISSN 0165-6090. - 2:6(1981 Apr), pp. 329-337.

Receptors for peanut agglutinin on a high percentage of human cord-blood lymphocytes : phenotype characterization of peanut-positive cells

S. Siena;A.G. Siccardi;
1981

Abstract

The results of this study show that a high percentage of human cord-blood lymphocytes bears receptors for peanut agglutinin. Determination of the presence of other lymphocyte markers (E rosettes, membrane immunoglobulins, alpha-naphthyl-acetate esterase, Ia antigens) in the peanut-positive cells indicated that they include both T and B cells. The peanut receptor, also expressed by blast cells of most acute, but not chronic, leukemias, seems to be a marker of immaturity for both T- and B-lymphocyte subsets in man as it is in the mouse.
Aging; B-Lymphocytes; Child, Preschool; Fetal Blood; Humans; Infant; Lectins; Peanut Agglutinin; Phenotype; Receptors, Mitogen; T-Lymphocytes; Thymus Gland
Settore MED/06 - Oncologia Medica
apr-1981
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/552913
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