The frequency of HLA-DRB1*15 polymorphism, which is strongly associated to multiple sclerosis, was investigated in 84 adult patients with chronic dysimmune polyneuropathy and 272 healthy controls. No significant differences were detected between cases and controls and, among patients, according to gender, peripheral nerve antigen antibody seropositivity, and electrophysiological features. A trend towards an increase of HLA-DRB1*11 in anti-MAG neuropathy was detected.
HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy / M. Gironi, F.R. Guerini, E. Beghi, G. Antonini, F. Martinelli-Boneschi, L. Ceresa, S. Morino, C. Agliardi, P. Ferrante, R. Nemni. - In: NEUROMUSCULAR DISORDERS. - ISSN 0960-8966. - 18:12(2008 Dec), pp. 967-969.
HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy
F. Martinelli-Boneschi;L. Ceresa;P. FerrantePenultimo
;R. NemniUltimo
2008
Abstract
The frequency of HLA-DRB1*15 polymorphism, which is strongly associated to multiple sclerosis, was investigated in 84 adult patients with chronic dysimmune polyneuropathy and 272 healthy controls. No significant differences were detected between cases and controls and, among patients, according to gender, peripheral nerve antigen antibody seropositivity, and electrophysiological features. A trend towards an increase of HLA-DRB1*11 in anti-MAG neuropathy was detected.
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