Atypical fibroxanthoma is an uncommon mesenchymal tumor that manifests clinically as a reddish papule or nodule in sun-exposed areas of the body. The clinical presentation is not specific and histology and immunohistochemistry are both necessary for a correct diagnosis. Surgery is the gold standard of therapy. Recurrence and metastasis should be excluded with a follow-up at 6 months, since this tumor should nowadays be considered a medium-grade neoplasm, rather than low-grade as previously believed. We report the case of two friends who came to our hospital during the same period, complaining of very similar lesions. After biopsy and immunohistochemical examination, a diagnosis of atypical fibroxanthoma in both cases was formulated.

Two friends with eroded nodules on the ears : Atypical fibroxanthoma case report / F. Pesapane, G. Nazzaro, L. Lunardon, A. Coggi, R. Gianotti. - In: ANAIS BRASILEIROS DE DERMATOLOGIA. - ISSN 0365-0596. - 90:4(2015 Aug), pp. 577-579. [10.1590/abd1806-4841.20153313]

Two friends with eroded nodules on the ears : Atypical fibroxanthoma case report

F. Pesapane
;
G. Nazzaro
Secondo
;
L. Lunardon;R. Gianotti
Ultimo
2015-08

Abstract

Atypical fibroxanthoma is an uncommon mesenchymal tumor that manifests clinically as a reddish papule or nodule in sun-exposed areas of the body. The clinical presentation is not specific and histology and immunohistochemistry are both necessary for a correct diagnosis. Surgery is the gold standard of therapy. Recurrence and metastasis should be excluded with a follow-up at 6 months, since this tumor should nowadays be considered a medium-grade neoplasm, rather than low-grade as previously believed. We report the case of two friends who came to our hospital during the same period, complaining of very similar lesions. After biopsy and immunohistochemical examination, a diagnosis of atypical fibroxanthoma in both cases was formulated.
immunohistochemistry; sarcoma; skin neoplasms; aged; biopsy; diagnosis, differential; ear auricle; ear neoplasms; fibroma; friends; humans; immunohistochemistry; male; skin neoplasms; xanthomatosis; 2708
Settore MED/35 - Malattie Cutanee e Veneree
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/519950
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