A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic esters of 2-iodophenols, is reported. The cytotoxic activity of these isoaurones is lower than that of the structurally very similar 4-arylcoumarins. (c) 2005 Elsevier Ltd. All rights reserved.
A new synthesis of isoaurones : cytotoxic activity of compounds related to the alleged structure of isoaurostatin / E. Rizzi, S. Dallavalle, L. Merlini, G.L. Beretta, G. Pratesi, F. Zunino. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 15:19(2005 Oct 01), pp. 4313-4316.
A new synthesis of isoaurones : cytotoxic activity of compounds related to the alleged structure of isoaurostatin
S. DallavalleSecondo
;L. Merlini;
2005
Abstract
A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic esters of 2-iodophenols, is reported. The cytotoxic activity of these isoaurones is lower than that of the structurally very similar 4-arylcoumarins. (c) 2005 Elsevier Ltd. All rights reserved.
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