BACKGROUND: Uterine artery Doppler pulsatility index (UtA-PI) may be different in pregnancies with egg donation (ICSI-ED) as compared to conceptions with autologous intra-cytoplasmatic sperm injection (autologous ICSI) and to spontaneous conceptions (SC). METHODS: One hundred and ninety-four pregnant women with different modes of conception (MC) were prospectively evaluated: 53 ICSI-ED, 36 autologous ICSI and 105 SC. To evaluate the effects of different MC on PI, multivariable linear regression (MLR) models predicting UtA-PI were fitted after adjustment for maternal age, body mass index, race, parity, smoking status and gestational age. RESULTS: In the first trimester, at MLR, autologous ICSI was not associated with a significantly different UtA-PI [estimate (EST) 0.01; 95% confidence interval (CI) -0.19, 0.2; P=0.9] when compared to SC. Conversely, MC by ICSI-ED was associated with lower first trimester UtA-PI (EST -0.32; CI -0.55, -0.08; P=0.01) when compared to SC. At MLR, MC by autologous ICSI and by ICSI-ED were not associated with significant differences in the second and third trimester UtA-PI when compared to SC. CONCLUSION: ICSI-ED conception presented lower UtA-PI when compared to SC at 11+0-13+6 weeks but not at later assessments. Correction of UtA-PI measurement specifying the origin of oocyte may be useful in first trimester screening.
Uterine artery Doppler pulsatility index at 11-38 weeks in ICSI pregnancies with egg donation / A. Inversetti, L. Mandia, M. Candiani, I. Cetin, A. Larcher, V. Savasi, E. Papaleo, P.I. Cavoretto. - In: JOURNAL OF PERINATAL MEDICINE. - ISSN 0300-5577. - 46:1(2018 Jan 26), pp. 21-27.
|Titolo:||Uterine artery Doppler pulsatility index at 11-38 weeks in ICSI pregnancies with egg donation|
MANDIA, LUCA (Secondo)
PAPALEO, ENRICO (Penultimo)
CAVORETTO, PAOLO IVO (Ultimo) (Corresponding)
|Parole Chiave:||Egg donation (ED); in vitro fertilization (IVF); intra-cytoplasmatic sperm injection (ICSI); pulsatility index; uterine artery Doppler|
|Settore Scientifico Disciplinare:||Settore MED/40 - Ginecologia e Ostetricia|
|Data di pubblicazione:||26-gen-2018|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1515/jpm-2016-0180|
|Appare nelle tipologie:||01 - Articolo su periodico|
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